76808-18-9 Usage
Uses
Used in Pharmaceutical Research:
9H-B-Carbolne-3-Carboxylic Acid Propyl Ester is used as a research compound for exploring its pharmacological properties, including its anti-inflammatory, antifungal, and antitumor effects. Its potential in the development of new drugs is being investigated due to these promising biological activities.
Used in Drug Development:
As a propyl ester of carbolinic acid, 9H-B-Carbolne-3-Carboxylic Acid Propyl Ester is utilized in the development of new pharmaceutical compounds. Its chemical structure provides insights into the design of drugs targeting various health conditions, particularly those related to inflammation, fungal infections, and cancer.
Used in Structure-Activity Relationship Studies:
9H-B-Carbolne-3-Carboxylic Acid Propyl Ester is employed as a valuable tool in studying the relationship between the chemical structure of carbolines and their biological activities. This helps researchers understand how specific structural features contribute to the compound's therapeutic effects, guiding the design of more effective and targeted pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 76808-18-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,8,0 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 76808-18:
(7*7)+(6*6)+(5*8)+(4*0)+(3*8)+(2*1)+(1*8)=159
159 % 10 = 9
So 76808-18-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H14N2O2/c1-2-7-19-15(18)13-8-11-10-5-3-4-6-12(10)17-14(11)9-16-13/h3-6,8-9,17H,2,7H2,1H3
76808-18-9Relevant academic research and scientific papers
SYNTHESIS OF 3,6-DISUBSTITUTED &β-CARBOLINES WHICH POSSESS EITHER BENZODIAZEPINE ANTAGONIST OR AGONIST ACTIVITY
Hagen, Timothy J.,Guzman, Filadelfo,Schultz, Christopher,Cook, James M.,Skolnick, Phil,Shannon, Harlan E.
, p. 2845 - 2855 (2007/10/02)
A series of 3-substituted and 3,6-disubstituted β-carbolines have been synthesized.These compounds have been screened in vitro in order to determine the size of substituents which benzodiazepine receptors will tolerate at positions -3 and -6 of the β-carboline nucleus.It has been found that the receptor will tolerate ester alkyl groups at position-3 as large as cyclohexyl 1g but not as large as adamantyl 5d.Moreover, N-aryl substituents as large as naphthobenzylamino 8b can be introduced at position-6 without significant loss of receptor binding affinity.
β-Carbolines as benzodiazepine receptor ligands. 1. Synthesis and benzodiazepine receptor interaction of esters of β-carboline-3-carboxylic acid
Lippke,Schunack,Wenning,Muller
, p. 499 - 503 (2007/10/02)
Several esters of β-carboline-3-carboxylic acid were synthesized and tested in respect to their affinity for the benzodiazepine receptor in bovine cortex membranes. Out of these derivatives, the methyl, ethyl, and n-propyl ester were clearly the most pote
