76811-96-6

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 4-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl-alpha,alpha-dimethylbenzeneacetate hydrochloride is used as a potential therapeutic agent for the treatment of certain medical conditions. Its unique structure suggests it may interact with specific biological targets, offering new avenues for drug development and treatment strategies.
Ethyl 4-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl-alpha,alpha-dimethylbenzeneacetate hydrochloride's exact applications and mechanisms of action would require further research to establish its safety, efficacy, and optimal use in medical treatments. As with any new pharmaceutical candidate, extensive testing and clinical trials would be necessary to validate its potential benefits and to understand any possible side effects or contraindications.

InChI:InChI=1/C34H41NO4.ClH/c1-4-39-32(37)33(2,3)27-19-17-26(18-20-27)31(36)16-11-23-35-24-21-30(22-25-35)34(38,28-12-7-5-8-13-28)29-14-9-6-10-15-29;/h5-10,12-15,17-20,30,38H,4,11,16,21-25H2,1-3H3;1H

Upstream product

• 76811-97-7 4-(4-chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic acid ethyl ester 
• 115-46-8 C₁₈H₂₁NO 

Relevant academic research and scientific papers

ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF

This invention relates to novel piperidine derivatives of formula (I) and a process for the preparation thereof, wherein R1 is H or C1-C6alkyl wherein the C1-C6alkyl moiety is straight or branched; R2 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; or stereoisomers or pharmaceutically acceptable acid addition salt thereof.

Antihistaminic piperidine derivatives and intermediates for the preparation thereof

This invention relates to novel piperidine derivatives of formula (I) and a process for the preparation thereof. wherein R1is H or C1-C6alkyl wherein the C1-C6alkyl moiety is straight or branched; R2is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; or stereoisomers or pharmaceutically acceptable acid addition salt thereof.

Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof

This invention relates to novel piperidine derivatives of formula (I) and a process for the preparation thereof. wherein R1 is H or C1-C6alkyl wherein the C1-C6alkyl moiety is straight or branched; R2 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; or stereoisomers or pharmaceutically acceptable acid addition salt thereof.

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula whereinW represents —C(=O)— or —CH(OH)—;R1 represents hydrogen or hydroxy;R2 represents hydrogen;R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2;n is an integer of from 1 to 5;m is an integer 0 or 1;R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof,with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.

Antihistaminic piperidine derivatives and intermediates for the preparation thereof

This invention relates to novel piperidine derivatives of formula (I) and a process for the preparation thereof.whereinR1 is H or C1-C6alkyl wherein the C1-C6alkyl moiety is straight or branched;R2 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; orstereoisomers or pharmaceutically acceptable acid addition salt thereof.

Piperidine derivatives

Pharmaceutically useful compounds of the following formula: STR1 wherein R1 represents hydrogen or hydroxy; R2 represents hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2 ; n is a positive whole integer of from 1 to 5; R3 is --CH3, --CH2 OH, --COOH or --COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; and A and B are individually hydrogen or hydroxy; with the provisos that at least one of A or B is hydrogen and one of A or B is other than hydrogen when R3 is --CH3 ; and pharmaceutically acceptable acid addition salts thereof.