7682-49-7

Basic information

• Product Name: Propanedioic acid, [[(phenylmethoxy)carbonyl]amino]-, monoethyl ester
• Synonyms: 2-benzyloxycarbonylaminomalonic acid monoethyl ester;Benzyloxycarbonylamino-malonsaeure-monoaethylester;benzyloxycarbonylamino-malonic acid monoethyl ester;Monoethyl N-benzyloxycarbonyl-2-aminomalonate
• CAS NO: 7682-49-7
• Molecular Formula: C13H15NO6
• Molecular Weight: 281.265
• Mol File: 7682-49-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, [[(phenylmethoxy)carbonyl]amino]-, monoethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, [[(phenylmethoxy)carbonyl]amino]-, monoethyl ester(7682-49-7)
• EPA Substance Registry System: Propanedioic acid, [[(phenylmethoxy)carbonyl]amino]-, monoethyl ester(7682-49-7)

Safety Data

• Hazardous Substances Data: 7682-49-7(Hazardous Substances Data)

Usage

Uses

Monoethyl (Benzyloxycarbonylamino)malonate is an intermediate in the synthesis of (±)-Biotin.

Upstream product

• 501-53-1 benzyl chloroformate 
• 13433-00-6 diethyl aminomalonate hydrochloride 
• 3005-66-1 diethyl 2-benzyloxycarbonylaminomalonate 

Downstream Products

• 50685-13-7 ethyl (Z)-α-N-benzyloxycarbonyl-α,β-didehydrophenylalaninate 
• 67218-74-0 2-benzyloxycarbonylaminopropane-N-methyldiamide 
• 88100-30-5 2-benzyloxycarbonylaminopropane-N-ethyldiamide 
• 67218-89-7 (Benzylcarbamoyl-carbamoyl-methyl)-carbamic acid benzyl ester 
• 88100-29-2 N^α-(carbobenzyloxy)-α-carbethoxyglycine N-ethylamide 
• 119183-73-2 N^α-(carbobenzyloxy)-L-valyl-α-carbethoxyglycine N-ethylamide 
• 264913-43-1 Ethyl 2-(N-benzyloxycarbonylamino)-2-tert-butoxycarbonylaminoethanoate 
• 255869-50-2 N-Benzyloxycarbonyl-2-carboxamidoglicine ethyl ether 
• 103711-23-5 α-<(tert-butyloxycarbonyl)amino>-N^α-(benzyloxycarbonyl)glycine 
• 1001165-13-4 ethyl ester of 3-[[2-(4-fluorophenoxy)ethyl]amino]-3-oxo-N-[(phenylmethoxy)carbonyl]alanine 
• 350238-04-9 2-benzyloxycarbonylamino-N-(5-chloro-2-phenylcarbamoylacetyl-phenyl)-malonamic acid ethyl ester 

Relevant articles and documents

Stereoselective synthesis of dehydroamino acids using malonic acid half oxyester and aromatic aldehydes

An efficient and direct approach was developed for the synthesis of α,β-dehydroamino acid derivatives with a broad range of substrates. Amido-substituted Malonic Acid Half Oxyesters (MAHOs) have proven to be excellent partners of various aromatic aldehyde

An electrochemical synthesis of 2-acetoxy-2-amino acid and 3-acetoxy-3-amino acid derivatives.

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