76822-62-3

Basic information

• Product Name: N-(4-{[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl](methyl)amino}benzoyl)glutamic acid
• CAS NO: 76822-62-3
• Molecular Formula: C₂₁H₂₃N₇O₅
• Molecular Weight: 453.4512
• Mol File: 76822-62-3.mol
• Article Data: 2

Chemical Properties

• Density: 1.499g/cm³
• Refractive Index: 1.731
• CAS DataBase Reference: N-(4-{[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl](methyl)amino}benzoyl)glutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-{[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl](methyl)amino}benzoyl)glutamic acid(76822-62-3)
• EPA Substance Registry System: N-(4-{[(2,4-diaminopyrido[3,2-d]pyrimidin-6-yl)methyl](methyl)amino}benzoyl)glutamic acid(76822-62-3)

Safety Data

• Hazardous Substances Data: 76822-62-3(Hazardous Substances Data)

Upstream product

• 76807-54-0 6-(Acetoxymethyl)-2,4-dioxopyrido<3,2-d>pyrimidine 
• 76807-55-1 6-(Acetoxymethyl)-2,4-dichloropyrido<3,2-d>pyrimidine 
• 76832-40-1 6-(Acetoxymethyl)-4-amino-2-chloropyrido<3,2-d>pyrimidine 
• 76807-53-9 2,4-Dioxo-6-methylpyrido<3,2-d>pyrimidine 5-Oxide 
• 76807-56-2 2,4-diamino-6-(bromomethyl)pyrido<3,2-d>pyrimidine 
• 76822-61-2 2,4-Diamino-6-(hydroxymethyl)pyrido<3,2-d>pyrimidine 
• 2499-96-9 2,4-Dioxo-6-methylpyrido<3,2-d>pyrimidine 
• 76807-60-8 diethyl N-[4-[(2,4-diaminopyrido[3,2-d]pyrimidin-6-ylmethyl)methylamino]benzoyl]-L-glutamate 

Relevant articles and documents

Mechanism-based design, synthesis and biological studies of N 5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents

A number of 8-deazatetrahydrofolates bearing electrophilic groups on N 5 were designed and synthesized based on the action mechanism of methionine synthase, and their biological activities were investigated as well. Compounds (11b, 12b and 16)