76825-69-9Relevant academic research and scientific papers
1,3-Dipolar cycloaddition reactions assisted by microwave radiation and gamma radiation
Kusurkar,Kannadkar
, p. 2235 - 2239 (2007/10/03)
Microwave irradiation and gamma irradiation are shown to be new and most suitable techniques for 1,3-dipolar reactions using unsaturated oximes with conventional dipolarophile.
Cycloaddition reactions of conjugated aldoximes and ketoximes using conventional dienophiles
Kusurkar,Gadre,Kulkarni
, p. 635 - 649 (2007/10/02)
Cycloaddition reactions of simple and substituted benzaldoximes and acetophenone oximes using conventional dienophiles were tried expecting [4+2] cycloadduct. However these reactions furnished new aryl substituted isoxazolidines.
X=Y-ZH Systems as Potential 1,3-Dipoles. Part 2. Oxime cycloadditions: formation of 2:1 Adducts
Grigg, Ronald,Jordan, Maurice,Tangthongkum, Aant,Einstein, Frederick W. B.,Jones, Terry
, p. 47 - 57 (2007/10/02)
Cycloaddition of aldehyde and ketone oximes are shown to give mixtures of all possible isoxazolidine regioisomers and stereoisomers.The products are 2:1 adducts with the second molecule of the dipolarophile attached to the isoxazolidine N-atom.The stereochemistry of the major isomer from benzaldehyde oxime and acrylonitrile was established by an X-ray crystal structure analysis.The cycloaddition is shown to be weakly catalysed by 2,4-dinitrophenol and to proceed best in acetonitrile.More polar solvents slightly favour the 5-isoxazolidine regioisomer.The mechanism of the reaction is discussed.
