2-Hydroxy-oestradiol-(17β), also known as 2-hydroxyestradiol-17β or 2-OH-E2, is a naturally occurring metabolite of the hormone estradiol, which is the most potent form of estrogen in humans. It plays a crucial role in various physiological processes, including the regulation of the menstrual cycle, pregnancy, and bone health. This chemical is formed through the metabolism of estradiol by the cytochrome P450 enzyme system, specifically by the action of the CYP1A1 and CYP1B1 enzymes. 2-Hydroxy-oestradiol-(17β) has been implicated in the development of certain diseases, such as breast cancer, due to its potential to form DNA-damaging metabolites. However, it also has beneficial effects, such as promoting bone mineral density and acting as an antioxidant. The balance of various metabolites, including 2-hydroxy-oestradiol-(17β), is essential for maintaining overall health and preventing disease.
The CAS Registry Mumber 7683-31-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,8 and 3 respectively; the second part has 2 digits, 3 and 1 respectively. Calculate Digit Verification of CAS Registry Number 7683-31: (6*7)+(5*6)+(4*8)+(3*3)+(2*3)+(1*1)=120 120 % 10 = 0 So 7683-31-0 is a valid CAS Registry Number.
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