76832-77-4

Basic information

• Product Name: 1-Benzyl-4-tert-butyl-piperidine 1-oxide
• CAS NO: 76832-77-4
• Molecular Weight: 247.381
• Mol File: 76832-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Benzyl-4-tert-butyl-piperidine 1-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyl-4-tert-butyl-piperidine 1-oxide(76832-77-4)
• EPA Substance Registry System: 1-Benzyl-4-tert-butyl-piperidine 1-oxide(76832-77-4)

Safety Data

• Hazardous Substances Data: 76832-77-4(Hazardous Substances Data)

Upstream product

• 7576-09-2 1-benzyl-4-tert-butyl-piperidine 

Relevant articles and documents

Stereoselectivity in the Formation of Heterocyclic Amine Oxides

The stereoselectivity of the oxidation of N-alkylpiperidines was studied with the aid of the conformationally biassing 4-tert-butyl substituent.The stereoselectivity was always >95percent and showed little sensitivity to the nature of the N-alkyl substituent.The axial approach was found to be predominating stereochemical oxidation path.A brief study of the effects of solvent, temperature, and oxidant on the stereoselectivity was made.The 1,4-dimethylpiperazine system was investigated, and its oxidation at room temperature resulted in 100percent of trans-1,4-dimethylpiperazine 1,4-dioxide.A method to modulate the stereoselectivity in the formation of saturated heterocyclic amine oxides was developed by inverting the sequence of introduction of the nitrogen substituents.With cis-8-methyl-8-azabicyclononane oxidation is preferred from that side of the molecule which is sterically more hindered.