768395-35-3

Upstream product

• 6453-07-2 (+/-)-trans-4-oxo-1,2-cyclopentanedicarboxylic acid bis(methyl ester) 
• 192385-73-2 (-)-trans-(7R,8R)-1,4-dithiaspiro[4.4]nonane-7,8-dicarboxylic acid dimethyl ester 
• 768395-31-9 (E)-(1S,8S,10R,12S,14S)-1-(tert-Butyl-dimethyl-silanyloxy)-15-(4-methoxy-benzyloxy)-1-[(1R,2R)-2-(2-methoxy-ethoxymethoxymethyl)-cyclopentyl]-8,10,12,14-tetramethyl-pentadec-3-en-5-yn-7-one 
• 768395-32-0 (E)-(1S,8S,10R,12S,14S)-1-(tert-Butyl-dimethyl-silanyloxy)-15-hydroxy-1-[(1R,2R)-2-(2-methoxy-ethoxymethoxymethyl)-cyclopentyl]-8,10,12,14-tetramethyl-pentadec-3-en-5-yn-7-one 
• 768395-20-6 tert-Butyl-[(2S,4R,6S,8S)-9-(4-methoxy-benzyloxy)-2,4,6,8-tetramethyl-nonyloxy]-diphenyl-silane 
• 768395-25-1 tert-Butyl-{(1R,2R)-2-[(S)-1-(4-methoxy-benzyloxy)-but-3-enyl]-cyclopentylmethoxy}-diphenyl-silane 
• 768395-18-2 ((2S,4R,6S,8S)-9-Benzyloxy-2,4,6,8-tetramethyl-nonyloxy)-tert-butyl-diphenyl-silane 
• 552298-37-0 (2S,4R,6S,8S)-9-Benzyloxy-2,4,6,8-tetramethyl-nonanoic acid ((1R,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide 
• 768395-19-3 (2S,4S,6R,8S)-2,4,6,8-tetramethyl-9-(tert-butyldiphenylsiloxy)nonan-1-ol 
• 768395-27-3 1-Methoxy-4-{(S)-1-[(1R,2R)-2-(2-methoxy-ethoxymethoxymethyl)-cyclopentyl]-but-3-enyloxymethyl}-benzene 
• 768395-28-4 (S)-3-(4-Methoxy-benzyloxy)-3-[(1R,2R)-2-(2-methoxy-ethoxymethoxymethyl)-cyclopentyl]-propionaldehyde 
• 768395-42-2 [(1R,2R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-cyclopentyl]-methanol 
• 768395-21-7 (2S,4R,6S,8S)-9-[(4-methoxybenzyl)oxy]-2,4,6,8-tetramethylnonan-1-ol 
• 768395-22-8 (1R,2R)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-cyclopentanecarbaldehyde 

Downstream Products

• 768395-36-4 (E)-(3S,4S,6S,8R,10S,17S)-17-(tert-Butyl-dimethyl-silanyloxy)-17-[(1R,2R)-2-(2-methoxy-ethoxymethoxymethyl)-cyclopentyl]-3-methoxymethoxy-4,6,8,10-tetramethyl-11-oxo-heptadec-14-en-12-ynoic acid 4-methoxy-benzyl ester 
• 768395-37-5 (E)-(3S,4S,6S,8R,10S,17S)-17-Hydroxy-17-[(1R,2R)-2-(2-methoxy-ethoxymethoxymethyl)-cyclopentyl]-3-methoxymethoxy-4,6,8,10-tetramethyl-11-oxo-heptadec-14-en-12-ynoic acid 4-methoxy-benzyl ester 
• 97328-74-0 (1R,2R)-2-((4E,6Z)-(2S,8S,9S,11R,13S,15S,16S)-7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-oxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecarboxylic acid 
• 7184-60-3 borrelidin 

Relevant academic research and scientific papers

Stereoselective total synthesis of (-)-borrelidin

A convergent synthesis of (-)-borrelidin (1) is reported based on the retrosynthetic disconnections indicated in the picture. Highlights of the strategy include the construction of a strained enynone-containing macrolide and the installation of a cyano group in a regioselective manner by a novel molybdenum-catalyzed hydrostannation of the alkyne.