76840-95-4

Upstream product

• 74864-74-7 2-(3,4,5-trimethoxyphenoxy)aniline 
• 54255-11-7 2-chloro-4,5-dihydro-1H-imidazole 
• 642-71-7 3,4,5-trimethoxyphenol 
• 104272-68-6 1-nitro-2-(3,4,5-trimethoxyphenoxy)benzene 
• 76838-20-5 1-Benzoyl-3-[2-(3,4,5-trimethoxy-phenoxy)-phenyl]-thiourea 
• 88-73-3 2-Chloronitrobenzene 
• 54255-12-8 2-Chloro-4,5-dihydro-1H-imidazole sulfate 

Relevant academic research and scientific papers

Carbon disulfide promoted reactions of 2-chloro-4,5-dihydro-imidazole with some n-nucleophiles

The reactions of 2-chloro-4,5-dihydroimidazole 1 with o-substituted anilines and azoles promoted by carbon disulfide have been carried out. Ab initio MO calculations were used to elucidate the mechanism of the reaction of 1 with N-nucleophilic reagents. A facile synthesis of 2-(4,5-dihydroimidazol-2-yl)-1H-indazole 3e bearing structural resemblances to 2-BFI, a potent and selective agonist of imidazoline I2 receptors, is also described. Structure of 3e was confirmed by NMR spectroscopy and X-ray analysis.