76843-23-7Relevant articles and documents
New application of tanshinone IIA derivatives as MAGL (monoacylglycerol lipase) inhibitor
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Paragraph 0012; 0029, (2017/09/12)
The invention relates to the field of pharmaceutical chemistry, specifically to medical application of tanshinone IIA derivatives (I) and (II). Pharmacological experiments show that the compound has strong monoacylglycerol lipase inhibitory activity and good analgesic activity. The compound is expected to be used for developing a novel analgesic drug based on the clinic use of a monoacylglycerol lipase inhibitor.
Radix Salviae Miltiorrhizae ketone compound, preparation method and its use (by machine translation)
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Paragraph 0107-0109, (2016/10/10)
The invention provides tanshinone compounds, a preparation method and use thereof, and relates to the technical field of pharmaceutical chemistry. The tanshinone compounds possess a structure formula I or II as shown in the specification. The use of the tanshinone compounds includes but not limited to anticancer drugs, particularly the treatment of prostate cancer and bladder cancer, and induction of androgen receptor antagonist activity when patients have androgen-related diseases, wherein the androgen-related diseases include but not limited to multi-disease, acne, and spermatogenesis without inhibition in need of suppressing spermatogenesis.