7685-69-0

Basic information

• Product Name: N-[(o-nitrophenyl)thio]-L-serine
• Synonyms: N-[(o-nitrophenyl)thio]-L-serine;N-[(2-Nitrophenyl)thio]-L-serine
• CAS NO: 7685-69-0
• Molecular Formula: C₉H₁₀N₂O₅S
• Molecular Weight: 258.2511
• EINECS: 231-691-9
• Mol File: 7685-69-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 499°Cat760mmHg
• Flash Point: 255.6°C
• Appearance: /
• Density: 1.55g/cm³
• Vapor Pressure: 8.89E-11mmHg at 25°C
• Refractive Index: 1.664
• CAS DataBase Reference: N-[(o-nitrophenyl)thio]-L-serine(CAS DataBase Reference)
• NIST Chemistry Reference: N-[(o-nitrophenyl)thio]-L-serine(7685-69-0)
• EPA Substance Registry System: N-[(o-nitrophenyl)thio]-L-serine(7685-69-0)

Safety Data

• Hazardous Substances Data: 7685-69-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H10N2O5S/c12-5-6(9(13)14)10-17-8-4-2-1-3-7(8)11(15)16/h1-4,6,10,12H,5H2,(H,13,14)/t6-/m0/s1

Upstream product

• 302-84-1 serin 
• 7669-54-7 2-nitrobenzenesulfenyl chloride 
• 56-45-1 L-serin 

Downstream Products

• 75816-63-6 Nps-Ser(Tos)-Leu-OBu^t 
• 75816-46-5 Nps-Ser-Leu-OBu^t 
• 82774-80-9 o-NPS-L-Ser-L-Glu(γ-Bzl)-OTcp(2,4,5) 

Relevant articles and documents

SYNTHESIS OF REGULAR POLYPEPTIDES INCLUDING POLYFUNCTIONAL AMINO ACIDS

Polypeptides of regular structure with the sequences His-Glu, Ser-Glu, Try-Glu, His-Tyr, and Glu-His have been synthesized by the 2,4,5-trichlorophenyl ester method.Polymerization was carried out in dimethyl sulfoxide and dimethylformamide.The polymers were purified by dialysis against water.In the process of synthesizing the monomers, the α-amino groups of the acids were protected by ortho-nitrophenylsulfenyl (o-NPS-), benzyloxycarbonyl (Z-), and tert-butoxycarbonyl (t-BOC-) groups.The imidazole group of histidine was Z-protected, and the γ-hydroxy group of glutamic acid and the phenolic OH group of tyrosine were benzyl-protected (Bzl-).