76877-34-4 Usage
Uses
Used in Chemical Synthesis:
7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin is used as a precursor for the preparation of maleimide and iodoacetamide derivatives of 3-phenylcoumarin fluorophore. These derivatives exhibit self-quenching properties until they react with thiol groups, at which point they regain their strong fluorescence. This characteristic makes them useful in the development of new compounds with potential applications in various fields.
Used in Analytical Chemistry:
As a fluorescent thiol-reactive neutral probe, 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin is employed in the detection and quantification of thiol-containing molecules. Thiols are essential components in many biological systems and are often involved in various cellular processes. The ability of 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin to selectively react with thiols and exhibit a significant change in fluorescence upon reaction makes it a valuable tool for researchers in analytical chemistry and biochemistry.
Used in Pharmaceutical Research:
The unique reactivity of 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin with thiol groups also makes it a promising candidate for the development of new drugs targeting thiol-containing enzymes or proteins. By incorporating 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin into drug molecules, researchers can potentially design therapies that specifically target these proteins, leading to more effective treatments for various diseases.
Used in Material Science:
The fluorescent properties of 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin can be exploited in the development of new materials with specific optical or sensing properties. For example, 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin could be used to create sensors that detect the presence of thiols in a given environment, or to develop materials that change their optical properties in response to the presence of thiol-containing molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 76877-34-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,8,7 and 7 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 76877-34:
(7*7)+(6*6)+(5*8)+(4*7)+(3*7)+(2*3)+(1*4)=184
184 % 10 = 4
So 76877-34-4 is a valid CAS Registry Number.
InChI:InChI=1/C22H23IN2O3/c1-4-25(5-2)17-10-11-18-14(3)21(22(27)28-19(18)12-17)15-6-8-16(9-7-15)24-20(26)13-23/h6-12H,4-5,13H2,1-3H3,(H,24,26)
