Camptothecin chloroacetate is a chemical derivative of the naturally occurring alkaloid camptothecin, which is found in the bark and leaves of the Camptotheca acuminata tree. It is a potent topoisomerase I inhibitor, a key enzyme involved in DNA replication, and has been widely studied for its anticancer properties. The chloroacetate modification enhances the solubility and stability of camptothecin, making it more suitable for pharmaceutical applications. This derivative has shown promise in preclinical studies for its ability to inhibit tumor growth and has been investigated in various cancer therapies, including colorectal, ovarian, and lung cancers. The improved pharmacokinetic properties of camptothecin chloroacetate compared to the parent compound may contribute to its potential as a more effective anticancer agent.
The CAS Registry Mumber 7688-65-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,8 and 8 respectively; the second part has 2 digits, 6 and 5 respectively. Calculate Digit Verification of CAS Registry Number 7688-65: (6*7)+(5*6)+(4*8)+(3*8)+(2*6)+(1*5)=145 145 % 10 = 5 So 7688-65-5 is a valid CAS Registry Number.
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