76884-33-8

Usage

Uses

Used in Pharmaceutical Synthesis:
3-(ChloroMethyl)isoquinoline hydrochloride is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to be readily incorporated into complex molecular structures, contributing to the development of new drugs with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, 3-(ChloroMethyl)isoquinoline hydrochloride is utilized as a reagent or starting material for the preparation of a wide range of organic compounds, taking advantage of its unique functional groups and reactivity.
Used in Medicinal Research:
3-(ChloroMethyl)isoquinoline hydrochloride is employed as a research tool in medicinal chemistry, where its structural features can be exploited to design and develop novel therapeutic agents with improved pharmacological properties.
Used in Agrochemical Research:
In agrochemical research, 3-(ChloroMethyl)isoquinoline hydrochloride is used as a building block for the creation of new agrochemicals, potentially leading to the development of more effective and environmentally friendly pesticides or herbicides.
Used in Chemical Intermediates Production:
3-(ChloroMethyl)isoquinoline hydrochloride is used as a chemical intermediate for the production of various specialty chemicals, leveraging its unique properties to create compounds with specific applications in different industries.

Upstream product

• 76884-34-9 3-Hydroxymethylisoquinoline 

Downstream Products

• 67123-97-1 (R,S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid 
• 57980-74-2 ethyl 1,2,3,4-tetrahydroisoquinoline-3-carboxylate hydrochloride 

Relevant academic research and scientific papers

Heterocyclic thiazole derivatives and pharmaceutical compositions comprising said derivatives

The invention concerns a thiazole of the formula I, STR1 wherein Q1 is an optionally substituted 6-membered monocyclic or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen atoms; X is oxy, thio, sulphinyl, sulphonyl or imino; Ar is phenylene which may optionally bear one or two substituents, or Ar is an optionally substituted 6-membered heterocyclene moiety continuing up to three nitrogen atoms; R1 is hydrogen, (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl or substituted (1-4C)alkyl; R2 is hydrogen, (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl or substituted (1-4C)alkyl or R2 is optionally substituted benzoyl; and Q2 is optionally substituted thiazolyl; or a pharmaceutically-acceptable salt thereof. The invention also concerns processes for the manufacture of a thiazole of the formula I and pharmaceutical compositions containing said thiazole.

Heterocyclic derivatives

The invention concerns a thiazole of the formula I, wherein Q1 is an optionally substituted 6-membered monocyclic or 10-membered bicyclic heterocyclic moiety containing one or two nitrogen atoms;, X is oxy, thio, sulphinyl, sulphonyl or imino;, Ar is phenylene which may optionally bear one or two substituents, or Ar is an optionally substituted 6-membered heterocyclene moiety contining up to three nitrogen atoms;, R1 is hydrogen, (1-6C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl or substituted (1-4C)alkyl;, R2 is hydrogen, (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl or substituted (1-4C)alkyl or R2 is optionally substituted benzoyl; and, Q2 is optionally substituted thiazolyl;, or a pharmaceutically-acceptable salt thereof. The invention also concerns processes for the manufacture of a thiazole of the formula I and pharmaceutical compositions containing said thiazole.