76888-40-9Relevant articles and documents
Stereo- and regioselectivity in the P450-catalyzed oxidative tandem difunctionalization of 1-methylcyclohexene
Roiban, Gheorghe-Doru,Agudo, Rubén,Reetz, Manfred T.
, p. 5306 - 5311 (2013/07/05)
The selective partial oxidation of small non-functionalized molecules using biocatalysis based on P450 monooxygenases is known to be difficult due to the expected poor regio- and stereoselectivity, but in this study it was nevertheless attempted. 1-Methyl
A [3,3]-sigmatropic process catalysed by acetate. The decarboxylative Claisen rearrangement
Bourgeois, Damien,Craig, Donald,Grellepois, Fabienne,Mountford, David M.,Stewart, Alan J. W.
, p. 483 - 495 (2007/10/03)
Allylic tosylacetates and tosylmalonates undergo acetate-catalysed decarboxylative Claisen rearrangement in the presence of N,O-bis(trimethylsilyl) acetamide. The homoallylic sulfones formed in these transformations correspond to the products of regiospecific allylation of sulfone-stabilised carbanions. A mechanistic rationale is proposed.
Lithium Aluminium Hydride Partially Decomposed with (-)-N-Methylephedrine and 2-Alkylaminopyridine: An Improved Chiral Hydride Useful for the Practical Asymmetric Reduction of Achiral Cyclic Ketones
Kawasaki, Motoji,Suzuki, Yasutaka,Terashima, Shiro
, p. 52 - 60 (2007/10/02)
The title chiral hydride was found to reduce various achiral cyclic ketons, giving the corresponding optically active cyclic (R)-alcohols in high optical (73-98percent) yields.The development of the improved chiral hydride and some characteristics of the reagent are also described.Keywords - asymmetric reduction; lithium aluminium hydride; (-)-N-methylephedrine; 2-alkylaminopyridine; 2-cyclohexen-1-one; achiral cyclic ketone; optically active cyclic alcohol
