76892-78-9

Basic information

• Product Name: Thiourea, N-(4-chlorophenyl)-N'-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-
• CAS NO: 76892-78-9
• Molecular Formula: C15H10ClN3O2S
• Molecular Weight: 331.782
• Mol File: 76892-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thiourea, N-(4-chlorophenyl)-N'-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-(4-chlorophenyl)-N'-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-(76892-78-9)
• EPA Substance Registry System: Thiourea, N-(4-chlorophenyl)-N'-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-(76892-78-9)

Safety Data

• Hazardous Substances Data: 76892-78-9(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 22814-92-2 4-(p-chlorophenyl)-3-thiosemicarbazide 
• 106-47-8 4-chloro-aniline 
• 1875-48-5 N-aminophthalamide 
• 2131-55-7 4-Chlorophenyl isothiocyanate 

Relevant articles and documents

Synthesis and anticonvulsant and neurotoxicity evaluation of N 4-phthalimido phenyl (thio) semicarbazides

The phenyl (thio) semicarbazide derivatives of phthalimido pharmacophore were synthesized and evaluated for their anticonvulsant and neurotoxic properties. Initial anticonvulsant screening was performed using intraperitoneal (i.p.), maximal electroshock-induced seizure (MES), subcutaneous pentylenetetrazole (scPTZ) and subcutaneous strychnine (sc STY)-induced seizure threshold tests in mice. Compound 2c afforded protection in all the three screens. Compounds except 1d, 2a and 2d showed no neurotoxicity up to 300mg/kg. Compounds 1a, 1b, 2c, 2d, 2g and 2i were found to show oral MES activity. The compounds exhibited CNS depression and behavioral despair side effects, lesser than the conventional antiepileptic drugs.

N-(arylthiocarbamoyl)-2-amino-1H-isoindole-1,3-(2H)diones and use as plant growth regulators

A novel class of compounds which are useful as plant growth regulators is disclosed, having the general structural formula: STR1 in which R1 is; C1 to C4 alkyl, nitro or halo and n is zero or an integer from 1 to 4 R2 and R3 are; H or C1 to C4 alkyl or hydroxyalkyl, or benzyl and Ar is; adamantyl, C3 to C4 alkyl or alkenyl, benzyl, halobenzyl, naphthyl, phenyl or phenyl bearing thereon from one to three of the substituents: cyano, benzyloxy, methylenedioxy, nitro, bromo, chloro, trifluoromethyl and C1 to C4 alkyl, alkenyl, alkoxy, alkylthio and alkyl-substituted amino.