769-05-1

Basic information

• Product Name: 2-chloro-6-fluorobenzenecarbothioamide
• Synonyms: 2-Chloro-6-fluorobenzenecarbothioamide; benzenecarbothioamide, 2-chloro-6-fluoro-
• CAS NO: 769-05-1
• Molecular Formula: C₇H₅ClFNS
• Molecular Weight: 189.6377
• Mol File: 769-05-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 280.145°C at 760 mmHg
• Flash Point: 123.227°C
• Density: 1.435g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 2-chloro-6-fluorobenzenecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-fluorobenzenecarbothioamide(769-05-1)
• EPA Substance Registry System: 2-chloro-6-fluorobenzenecarbothioamide(769-05-1)

Safety Data

• Hazardous Substances Data: 769-05-1(Hazardous Substances Data)

Upstream product

• 668-45-1 2-chloro-6-fluorobenzonitrile 

Downstream Products

• 265652-35-5 methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate 
• 265652-40-2 Methyl 2-chloro-6-fluoro-N-[(4-bromo-3-methyl-2-thiophene)carbonyl]benzenecarboximidothioate 
• 265326-57-6 methyl 2-chloro-6-fluorobenzthioimidate 
• 503309-13-5 2-chloro-6-fluorothiobenzimidic acid methyl ester hydrogen bromide 
• 1620790-10-4 ethyl 4-(2-chloro-6-fluorophenyl)thiazole-2-carboxylate 
• 1365991-96-3 4-bromo-2-(2-chloro-6-fluorophenyl)thiazolo[5,4-c]pyridine 
• 1365991-95-2 2-(2-chloro-6-fluorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one 
• 1365991-94-1 (E)-3-(2-(2-chloro-6-fluorophenyl)thiazol-4-yl)acryloyl azide 
• 1365991-93-0 (E)-3-(2-(2-chloro-6-fluorophenyl)thiazol-4-yl)acryloyl chloride 
• 1365991-92-9 (E)-3-(2-(2-chloro-6-fluorophenyl)thiazol-4-yl)acrylic acid 
• 1365991-91-8 (E)-methyl 3-(2-(2-chloro-6-fluorophenyl)thiazol-4-yl)acrylate 
• 1248807-52-4 2-(2-chloro-6-fluorophenyl)thiazole-4-carbaldehyde 
• 1176514-65-0 (2-(2-chloro-6-fluorophenyl)thiazol-4-yl)methanol 
• 1365989-41-8 N-(2-(2-chloro-6-fluorophenyl)thiazolo[5,4-c]pyridin-4-yl)cyclopropanecarboxamide 

Relevant articles and documents

AZABENZOTHIAZOLE COMPOUNDS, COMPOSITIONS AND METHODS OF USE

Provided are compounds of Formula I, stereoisomers, tautomers, solvates, prodrugs and pharmaceutically acceptable salts thereof, wherein A, X, R1, R2, R4 and R5 are defined herein, a pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, methods of using the compound or composition in therapy, and methods of 5 manufacturing a compound of Formula I

Reactions of some ortho and para halogenated aromatic nitriles with ethylenediamine: Selective synthesis of imidazolines

The reaction of ethylenediamine (EDA) with ortho and/or para halogenated benzonitriles did not lead to the imidazolines expected: a competitive aromatic nucleophilic substitution (SNAr) was observed instead. The selective synthesis of these imidazolines was performed by nucleophilic addition of EDA to thiobenzamide derivatives. The difference in reactivity between the nitrile and thioamide derivatives was estimated by a frontier orbital approach at the RHF/6-31G** level which predicted a greater reactivity of substituted thiobenzamides towards the nucleophilic addition of EDA.

3-(substituted phenyl)-5-thienyl-1,2,4-triazole compounds with activity against whitefly

3-(Substituted phenyl)-5-(thienyl)-1,2,4-triazole compounds are useful as insecticides and acaricides.