76904-97-7Relevant academic research and scientific papers
Bellisosides A-F, six novel acylated triterpenoid saponins from Bellis perennis (compositae)
Li, Wei,Asada, Yoshihisa,Koike, Kazuo,Nikaido, Tamotsu,Furuya, Tsutomu,Yoshikawa, Takafumi
, p. 2921 - 2929 (2007/10/03)
Six new acylated triterpenoid saponins, bellisosides A-F (1-6), were isolated from the roots of Bellis perennis (Compositae) together with a known saponin, bellissaponin BS2 (7). These saponins which bear polygalacic acid as sapogenin, are bisdesmosidic glycosides. The structures were elucidated on the basis of chemical and physicochemical evidence. The cytotoxic activities of 1-7 against HL-60 human promyelocytic leukemia cells are also reported.
Resin glycosides. XVIII. Determination by Mosher's method of the absolute configurations of mono- and dihydroxyfatty acids originated from resin glycosides
Ono,Yamada,Noda,Kawasaki,Miyahara
, p. 1023 - 1026 (2007/10/02)
The absolute configurations of four hydroxyfatty acids, jalapinolic acid, convolvulinolic acid, ipurolic acid and 3,11-dihydroxyhexadecanoic acid, obtained by acid hydrolysis of various resin glycosides, have been determined to be 11S,11S,3S,11S, and 3S,11S, respectively, by Mosher's method. The R- configuration of jalapinolic acid previously defined by Horeau's method was therefore revised to S.
Asymmetric Hydrogenation of 3,5-Dioxoesters Catalyzed by Ru-binap Complex: A Short Step Asymmetric Synthesis of 6-Substituted 5,6-dihydro-2-pyrones
Shao, Liming,Kawano, Hiroyuki,Saburi, Masahiko,Uchida, Yasuzo
, p. 1997 - 2010 (2007/10/02)
Asymmetric hydrogenation of 3,5-dioxoesters 1a-c using Ru2Cl4((R) or (S)-binap)2(NEt3) as the catalyst gave dominantly anti 3,5-dihydroxyesters 2, which were then converted into unsaturated lactones 5a-b (ca. 80percent e.e.).The pathway of the hydrogenation reaction was also investigated by asymmetric hydrogenation of (R)- or (S)-5-hydroxy-3-oxoesters 8a-c.It was revealed that the Ru-binap catalyzed hydrogenation of 1a-b proceed dominantly via the β-diketone mode.A convenient asymmetric synthesis of hydroxylactone 3c and unsaturated lactone 5c was presented.Key words: 3,5-dioxoester; Ru-binap catalyst; asymmetric hydrogenation; asymmetric synthesis; lactone
