769069-45-6

Basic information

• Product Name: Carbamic acid, chloro-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, chloro-, 1,1-dimethylethyl ester (9CI);tert-butyl chlorocarbamate
• CAS NO: 769069-45-6
• Molecular Formula: C₅H₁₀ClNO₂
• Molecular Weight: 151.5914
• Product Categories: N-BOC
• Mol File: 769069-45-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.124±0.06 g/cm3(Predicted)
• PKA: 5.84±0.46(Predicted)
• CAS DataBase Reference: Carbamic acid, chloro-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, chloro-, 1,1-dimethylethyl ester (9CI)(769069-45-6)
• EPA Substance Registry System: Carbamic acid, chloro-, 1,1-dimethylethyl ester (9CI)(769069-45-6)

Safety Data

• Hazardous Substances Data: 769069-45-6(Hazardous Substances Data)

Upstream product

• 4248-19-5 tert-butyl carbazate 

Downstream Products

• 4248-19-5 tert-butyl carbazate 
• 88000-67-3 tert-butyl benzoylimidocarboxylate 
• 2528-61-2 Heptanoic acid chloride 
• 1094070-77-5 (2-bromo-thiazol-5-yl)-carbamic acid tert-butyl ester 
• 170961-15-6 tert-butyl 1,3-thiazole-2-yl-carbamate 
• 1244041-71-1 2-tert-butoxycarbonylamino-6-bromobenzo[d]thiazole 
• 179626-68-7 N-(tert-butoxycarbonyl)-2-aminobenzothiazole 
• 148857-98-1 N-<(tert-butyloxy)carbonyl>-2-fluoro-6-nitroaniline 
• 745833-17-4 tert-butoxycarbonylamino-2,6-difluorobenzene 

Relevant articles and documents

N-Chloro- N-sodio-carbamates as a Practical Amidating Reagent for Scalable and Sustainable Amidation of Aldehydes under Visible Light

Herein, we describe the scalability and sustainability investigations toward the visible light-mediated amidation of aldehydes with N-chloro-N-sodio-carbamates. The practicality credentials of N-chloro-N-sodio-carbamates for their use in multigram scale a

Synthesis of 8-Aminoquinolines by Using Carbamate Reagents: Facile Installation and Deprotection of Practical Amidating Groups

Described herein is the development of practical routes to 8-aminoquinolines by using readily installable and easily deprotectable amidating reagents. Two scalable procedures were optimized under RhIII-catalyzed conditions: i) the use of pre-generated chlorocarbamates and ii) a two-step one-pot process that directly employs carbamates. Both approaches are highly convenient for the gram-scale synthesis of 8-aminoquinolines under mild conditions. Facile deprotection of the synthetically versatile amidating groups was achieved under the Pd-catalyzed transfer hydrogenation conditions with simultaneous deoxygenation of quinoline N-oxides, thus yielding 8-aminoquinolines in excellent overall efficiency.

Aziridination of C60 with simple amides and catalytic rearrangement of the aziridinofullerenes to azafulleroids

The selective formation of aziridinofullerene and azafulleroid, which are isomers of the fullerene derivatives-introduced N1 unit, is achieved. The ionic aziridination is a very convenient and risk-free procedure compared with the conventional