76916-60-4Relevant academic research and scientific papers
Novel gallium-mediated C3-allylation of indoles and pyrroles in aqueous media promoted by Bu4NBr
Prajapati, Dipak,Gohain, Mukut,Gogoi, Baikuntha J.
, p. 3535 - 3539 (2006)
A mild and efficient protocol for the coupling of indoles and pyrroles with allyl halides such as allyl bromide, crotyl bromide and propargyl bromide in the presence of gallium metal in a Bu4NBr-DMF-H2O system has been developed. The reaction is equally effective when cadmium is used in lieu of gallium and the corresponding 3-allyl indoles and 3-allyl pyrroles were obtained in almost comparable yields.
