Nafarelin acetate is a synthetic peptide and a potent agonist of gonadotropin-releasing hormone (GnRH). It is a long-acting agent that initially increases sex hormone levels but subsequently decreases the levels of circulating gonadotropins and sex hormones. Nafarelin acetate has been found to reduce plasma levels of luteinizing hormone and testosterone, as well as testicular volume, sperm count, sperm motility, and duration of ejaculation in male dogs. It also inhibits estrus in female beagle dogs and reduces the volume of endometrial tissue in a rat model of endometriosis.
Used in Pharmaceutical Industry:
Nafarelin acetate is used as a therapeutic agent for the treatment of endometriosis and central precocious puberty. It works by suppressing the production of sex hormones, which helps to alleviate the symptoms of these conditions.
Used in Veterinary Medicine:
Nafarelin acetate is used as a contraceptive agent in male dogs to reduce testicular volume, sperm count, sperm motility, and duration of ejaculation. It is also used in female beagle dogs to inhibit estrus and reduce the volume of endometrial tissue in a rat model of endometriosis.
Used in Research Applications:
Nafarelin acetate is used as a research tool to study the effects of GnRH agonists on the reproductive system and to investigate the mechanisms underlying the regulation of gonadotropin and sex hormone production. It can also be used to develop new formulations and drug delivery systems for the treatment of endometriosis and central precocious puberty.

76932-60-0

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Basic information
1. Product Name: Nafarelin acetate
2. Synonyms: Nafarelin acetate(76932-56-4 free base);Luteinizing hormone-releasing factor (pig), 6-[3-(2-naphthalenyl)-D-alanine]-, acetate (salt)
3. CAS NO:76932-60-0
4. Molecular Formula: C66H83N17O13.C2H4O2
5. Molecular Weight: 1382.54
6. EINECS: N/A
7. Product Categories: N/A
8. Mol File: 76932-60-0.mol
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: Nafarelin acetate(CAS DataBase Reference)
10. NIST Chemistry Reference: Nafarelin acetate(76932-60-0)
11. EPA Substance Registry System: Nafarelin acetate(76932-60-0)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 76932-60-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 76932-60-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,9,3 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 76932-60:
(7*7)+(6*6)+(5*9)+(4*3)+(3*2)+(2*6)+(1*0)=160
160 % 10 = 0
So 76932-60-0 is a valid CAS Registry Number.

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