76936-44-2

Basic information

• Product Name: N-(2-amino-1,1-dimethylethyl)-N,N-dimethylamine
• Synonyms: N-(2-amino-1,1-dimethylethyl)-N,N-dimethylamine;(2-amino-1,1-dimethylethyl)dimethylamine(SALTDATA: FREE);(2-amino-1,1-dimethylethyl)dimethylamine;N2,N2,2-TriMethylpropane-1,2-diaMine;N2,N2,2-trimethylpropane-1,2-diamine 2HCl
• CAS NO: 76936-44-2
• Molecular Formula: C₆H₁₆N₂
• Molecular Weight: 116.21
• Mol File: 76936-44-2.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 122.898°C at 760 mmHg
• Flash Point: 24.494°C
• Appearance: /
• Density: 0.839g/cm³
• Vapor Pressure: 13.655mmHg at 25°C
• Refractive Index: 1.448
• PKA: 9.68±0.10(Predicted)
• CAS DataBase Reference: N-(2-amino-1,1-dimethylethyl)-N,N-dimethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-amino-1,1-dimethylethyl)-N,N-dimethylamine(76936-44-2)
• EPA Substance Registry System: N-(2-amino-1,1-dimethylethyl)-N,N-dimethylamine(76936-44-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 76936-44-2(Hazardous Substances Data)

Usage

General Description

N-(2-amino-1,1-dimethylethyl)-N,N-dimethylamine, also known as DMF-DMA, is a chemical compound that falls under the category of a tertiary amine. It is commonly used as a catalyst in various chemical reactions, such as the synthesis of pharmaceuticals and agrochemicals. DMF-DMA is a colorless liquid with a strong ammonia-like odor and is highly soluble in water. It is known for its ability to act as a strong base, making it useful in organic synthesis reactions. However, it is important to handle and use this chemical with caution as it is known to be corrosive to the skin, eyes, and respiratory system. Additionally, it is flammable and should be kept away from open flames or other sources of ignition.

InChI:InChI=1/C6H16N2/c1-6(2,5-7)8(3)4/h5,7H2,1-4H3

Upstream product

• 2273-40-7 2-dimethylamino-2-methylpropionitrile 
• 60-29-7 diethyl ether 
• 98275-70-8 α-dimethylamino-isobutyraldehyde-oxime 

Downstream Products

• 1333535-23-1 C₁₈H₂₅FN₂O₃ 

Relevant articles and documents

Optical Resolution and Circular Dichroism Spectra of Mixed-diamine Palladium(II) Complexes with Configurational Chirality

Six square-planar complexes, (ClO4)2 (meso-stien = meso-1,2-diphenyl-1,2-ethanediamine; L = N,N-diethylethylenediamine, N,N-dimethylethylenediamine, 2-methyl-1,2-propanediamine, N2,N2-dimethyl-2-methyl-1,2-propanediamine, N,N-dimethyl-1,3-propenediamine, and (2S)-N1,N1-diethyl-1,2-propanediamine), were prepared and optically resolved (or separated in the case of the last named ligand) using diacetyl-d-tartaric anhydride as the resolving agent.Their electronic absorption and CD spectra were measured.A definite additivity has been confirmed between the configurational CD caused by the chiral configuration and the vicinal CD due to the asymmetric carbon atom in the (2S)-N1,N1-diethyl-1,2-propanediamine complex.Absolute configurations of this and the other five complexes have been assigned by examining molecular models and the CD spectra.

Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation, and methods for their use

Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.