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8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT is a chemical compound derived from adenosine, a nucleoside that plays a crucial role in cellular energy transfer and signal transduction. This specific compound features a bromine atom at the 8th position and is in the form of a sodium salt, which allows for its use in various biological and medical applications.

76939-46-3

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76939-46-3 Usage

Uses

Used in Cellular Research:
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT is used as a research tool for studying its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell culture. This helps scientists understand the role of 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT in cellular processes and its potential applications in medicine.
Used in Cancer Treatment Research:
In the field of oncology, 8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT is used to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis, and morphological changes in the nuclei. This research is crucial for developing new therapeutic strategies against cancer.
Used in Endocrinology Research:
8-BROMOADENOSINE-3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT is also used in superfusion medium for head kidneys stimulation, which is important for studying the endocrine system and its response to various stimuli. This application aids in understanding the compound's role in hormone production and regulation.

Biological Activity

Cell-permeable cAMP analog; activator of protein kinase A. Also available as part of the PKA Tocriset? .

Biochem/physiol Actions

Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.

Check Digit Verification of cas no

The CAS Registry Mumber 76939-46-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,9,3 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 76939-46:
(7*7)+(6*6)+(5*9)+(4*3)+(3*9)+(2*4)+(1*6)=183
183 % 10 = 3
So 76939-46-3 is a valid CAS Registry Number.

76939-46-3 Well-known Company Product Price

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  • Sigma

  • (B7880)  8-Bromoadenosine3′,5′-cyclicmonophosphatesodiumsalt  ≥97% (HPLC), powder

  • 76939-46-3

  • B7880-5MG

  • 375.57CNY

  • Detail
  • Sigma

  • (B7880)  8-Bromoadenosine3′,5′-cyclicmonophosphatesodiumsalt  ≥97% (HPLC), powder

  • 76939-46-3

  • B7880-25MG

  • 1,212.12CNY

  • Detail
  • Sigma

  • (B7880)  8-Bromoadenosine3′,5′-cyclicmonophosphatesodiumsalt  ≥97% (HPLC), powder

  • 76939-46-3

  • B7880-100MG

  • 3,597.75CNY

  • Detail
  • Sigma

  • (B7880)  8-Bromoadenosine3′,5′-cyclicmonophosphatesodiumsalt  ≥97% (HPLC), powder

  • 76939-46-3

  • B7880-250MG

  • 7,230.60CNY

  • Detail

76939-46-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-Bromo-cAMP, sodium salt,8-Bromoadenosine-3',5'-cyclicmonophosphatesodiumsalt

1.2 Other means of identification

Product number -
Other names 8-bromoadenosine 3:5-cyclic*monophosphate sodiu

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76939-46-3 SDS

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