76946-04-8Relevant articles and documents
PROCESS FOR PREPARING AN E-SELECTIN INHIBITOR INTERMEDIATE
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Paragraph 0052, (2021/02/26)
A process is provided for the synthesis of an intermediate of Formula 15 which is useful in the synthesis of E-selectin inhibitors. Also provided are useful intermediates obtained from the process.
Kilogram scale chemical synthesis of 2′-fucosyllactose
Agoston, Karoly,Hederos, Markus Jondelius,Bajza, Istvan,Dekany, Gyula
, p. 71 - 77 (2019/03/26)
A scalable synthetic procedure to high quality 2′-fucosyllactose, the most abundant oligosaccharide in human breast milk, has been designed and validated in kilogram scale. The synthetic route has been developed to suit industrial environment and contains
Synthesis and biological evaluation of E-selectin antagonists that present different carbohydrate ligands in a multivalent format
Thoma, Gebhard,Schwarzenbach, Franz
, p. 1491 - 1495 (2007/10/03)
The synthesis of the first polylysine conjugates that present different carbohydrate ligands in a multivalent format is reported. Glycopolymers 3c and 3d have been prepared with a highly predictable composition as indicated by 1H NMR. They func