76947-97-2Relevant academic research and scientific papers
A lanthanide(III) triflate mediated macrolactonization/solid-phase synthesis approach for depsipeptide synthesis
Goodreid, Jordan D.,Dos Santos Da Silveira, Eduardo,Batey, Robert A.
supporting information, p. 2182 - 2185 (2015/05/13)
The effect of dysprosium(III) triflate on macrolactonization reactions to form depsipeptides using MNBA (Shiina's reagent) is reported. Improved yields were obtained for the formation of 16-membered depsipeptides using lanthanide triflate additives. The use of a macrocyclization strategy permits the use of a semiautomated solid-phase synthesis approach for the rapid synthesis of analogues of the antibacterial A54556 acyldepsipeptides in only two physical operations, requiring only final product purification after cyclization.
Discovery of dipeptide-derived catalysts for the enantioselective addition of dimethylzinc to aldehydes
Kang, Seock Yong,Park, Yong Sun
supporting information; experimental part, p. 1703 - 1706 (2012/05/04)
A new class of modular chiral catalysts derived from various amino acid-L-Pro dipeptides was prepared, and the catalysts were tested for their ability to catalyze the enantioselective addition of dimethylzinc to aromatic aldehydes. Dipeptides derived from L-Asp-L-Pro were identified as effective catalysts for the addition at room temperature with up to 97:3er and 95% yield.
Le chloroformiate d'isopropenyle (IPCF) en chimie des peptides. II. Application a la synthese d'oligopeptides preparations de la tuftsine et de la bradykinine
Jaouadi, Mahmoud,Selve, Claude,Dormoy, Jean-Robert,Castro, Bertrand
, p. 870 - 874 (2007/10/02)
Isopropenyl chloroformate has been proved to be very suitable for dipeptides synthesis (1).We have extended the field of application of this reagent to the oligopeptides synthesis for mixed-anhydride method at ambient temperature.Interesting results were obtained in the preparation of tuftsin and bradykinin.
Le chloroformiate d'isopropenyle (IPCF) en chimie des peptides. I. Un bon reactif pour le couplage peptidique : synthese de dipeptides modeles
Jaouadi, M.,Selve, C.,Dormoy, J. R.,Castro, B.
, p. 409 - 412 (2007/10/02)
Isopropenyl chloroformate was used as an activating agent of N-protected amino-acids in the mixed anhydride method.This new reagent allows to run mixed anhydrides couplings at room temperature.
Synthesis and Carbon 13 N.M.R. Spectrum of the Peptide Fragment of Myelin Basic Protein (Human)
Pasaribu, Stephanus J.
, p. 2427 - 2440 (2007/10/02)
The tridecapeptide Phe-Lys-Leu-Gly-Gly-Arg-Asp-Ser-Arg-Ser-Gly-Ser-Pro-OH, and its methyl ester derivative at the carbonyl terminal, -Pro-OMe, were synthesized by the solution phase method.The synthesis was accomplished by fragment condensation of a tetra
