7695-47-8

Basic information

• Product Name: 3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one
• Synonyms: 3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one;8-Hydroxy-3,4-dihydro-2H-naphthalen-1-one;1,2,3,4-Tetrahydro-8-hydroxynaphthyl-1-one;8-Hydroxy-1-tetralone;8-Hydroxy-1-tetralone 8-Hydroxy-3,4-dihydro-2H-naphthalen-1-one;3,4-dihydro-8-hydroxy-1(2H)-Naphthalenone;8-hydroxy-3,4-dihydronaphthalen-1(2H)-one
• CAS NO: 7695-47-8
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.187
• Mol File: 7695-47-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 327.7°C at 760 mmHg
• Flash Point: 139.2°C
• Appearance: /
• Density: 1.236g/cm³
• Vapor Pressure: 0.000104mmHg at 25°C
• Refractive Index: 1.602
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.35±0.20(Predicted)
• CAS DataBase Reference: 3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one(7695-47-8)
• EPA Substance Registry System: 3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one(7695-47-8)

Safety Data

• Hazardous Substances Data: 7695-47-8(Hazardous Substances Data)

Usage

General Description

3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one, also known by its chemical formula C11H10O2, is a synthetic organic compound commonly used in the production of pharmaceuticals, dyes, and fragrances. It is a yellowish solid with a melting point of 114-115°C and has been identified as a key intermediate in the synthesis of various bioactive molecules, including anti-inflammatory and antitumor agents. Additionally, 3,4-Dihydro-8-hydroxynaphthalen-1(2H)-one has been found to exhibit antioxidant properties, making it a potential candidate for use in the formulation of skincare products. Its versatile applications and unique chemical properties make it an important compound in the field of organic chemistry and pharmaceutical research.

InChI:InChI=1/C10H10O2/c11-8-5-1-3-7-4-2-6-9(12)10(7)8/h1,3,5,11H,2,4,6H2

Upstream product

• 119-64-2 tetralin 

Downstream Products

• 88058-45-1 8-benzyloxy-1,2,3,4-tetrahydro-1-naphthalenone 
• 5656-61-1 4,5-dihydro-3H-naphtho<1,8-bc>furan 
• 32744-30-2 2-phenyl-4,5-dihydro-3H-naphtho<1,8-bc>furan 
• 133601-17-9 8-(1-hydroxy-1-phenylmethyl)-1,2,3,4-tetrahydro-1-naphthalenone 

Relevant articles and documents

Liquid-phase oxidation of alkylaromatics to aromatic ketones with molecular oxygen over a Mn-based metal-organic framework

Liquid-phase oxidation of alkylaromatics with molecular O2 was examined using a microporous Mn-based metal-organic framework (Mn-MOF-74). Mn-MOF-74 consisting of trimeric Mn clusters and 2,5-dihydroxyterephthalate (dhtp) linkers exhibits superior catalytic activity with good ketone selectivity compared to conventional oxide-supported Mn catalysts without showing any lengthy induction period. Combined analyses by means of XRD, FE-SEM, N2 physisorption and Mn K-edge XAFS reveal that the superior catalytic performance is attributed to the inherently-formed Mn(iii)2(dhtp) moieties embedded in the Mn-MOF-74 framework rather than structural factors associated with the MOF. The catalyst is reusable over multiple catalytic runs along with retaining its original catalytic activity due to the ability of the dhtp ligand to stabilize active Mn(iii) atoms. Owing to high activity, reusability and nontoxicity, Mn-MOF-74 can offer a simple, inexpensive and efficient protocol for the oxidation of some important alkylaromatics, such as ethylbenzene and diphenylmethane to produce the corresponding aromatic ketones.