76951-67-2Relevant academic research and scientific papers
Reactivity of 1,2-O-cyanoalkylidene sugar derivatives in trityl-cyanoalkylidene condensation
Kitov, P. I.,Tsvetkov, Yu. E.,Backinowsky, L. V.,Kochetkov, N. K.
, p. 1423 - 1428 (2007/10/02)
The rate-determining step of trityl-cyanoalkylidene condensation is the interaction between the cyanoalkylidene derivative (CD) and the triphenylmethyl cation.The rate of the reaction follows first-order kinetics with respect to both CD and the catalyst (Tr+) and is independent of the nature and condensation of the trityl ether.Glycosylation rate constants have been determined for CD's most common monosaccharides. - Key words: trityl-cyanoalkylidene condensation; cyanoalkylidene derivatives, mechanism of glycosidation.
A new stereospecific method for 1,2-cis-glycosylation
Kochetkov, Nicolay K.,Klimov, Evgeny M.,Malysheva, Nelly N.,Demchenko, Alexey V.
, p. 77 - 91 (2007/10/02)
A new stereospecific method for 1,2-cis-glycosylation involves the reaction of 1,2-trans-glycosyl thiocyanates with sugar trityl ethers in the presence of triphenylmethylium perchlorate.The method has been applied to give disaccharide derivatives with (1->6), (1->4), (1->3), and (1->2) linkages.
NOVEL HIGHLY STEREOSPECIFIC METHOD OF 1,2-CIS-GLYCOSYLATION. SYNTHESIS OF α-D-GLUCOSYL-D-GLUCOSES
Kochetkov, Nikolay K.,Klimov, Evgeny M.,Malysheva, Nelly N.
, p. 5459 - 5462 (2007/10/02)
Triphenylmethylium perchlorate-catalysed glycosylation of 2-, 3-, 4-, and 6-O-trityl-D-glucose derivatives with β-D-glucopyranosyl thiocyanates bearing a nonparticipating substituent at O-2 affords stereospecific derivatives of α-D-glucosyl-D-glucose
