76963-04-7

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 611-70-1 phenyl isopropyl ketone 
• 10409-54-8 2-bromo-2-methyl-1-phenyl-propan-1-one 
• 5703-26-4 4-Methoxyphenylacetaldehyde 
• 105-13-5 4-Methoxybenzyl alcohol 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 76963-11-6 (1S,3R)-3-(4-Methoxy-phenyl)-2,2-dimethyl-1-phenyl-cyclopropanethiol 
• 76963-12-7 (1S,3S)-3-(4-Methoxy-phenyl)-2,2-dimethyl-1-phenyl-cyclopropanethiol 
• 76963-05-8 3-(p-methoxyphenyl)thiopivalophenone 

Relevant academic research and scientific papers

Building Congested Ketone: Substituted Hantzsch Ester and Nitrile as Alkylation Reagents in Photoredox Catalysis

For the first time, 4-alkyl Hantzsch esters were used to construct molecules with all-carbon quaternary centers by visible light-induced photoredox catalysis via transfer alkylation. Up to a 1500 h-1 turnover frequency was achieved in this reaction. Reactions of 4-alkyl Hantzsch nitriles as tertiary radical donors joined two contiguous all-carbon quaternary centers intermolecularly, and this chemistry was used to synthesize a common precursor of a class of hydroxysteroid dehydrogenase inhibitors.

Thione photochemistry: Abstraction and cyclization at the β-position of aralkyl thiones from two excited states

Excitation of a series of β-substituted aralkyl thiones either to the S2 (π,π*) state or to the S1 (n,π*) state leads to a formal insertion into the β-position and the formation of cyclopropyl thiols. The mechanisms of intramolecular