76963-61-6Relevant academic research and scientific papers
(Butylthio)carbonyl Group: A New Protecting Group for the Guanine Residue in Oligoribonucleotide Synthesis
Fujii, Masayo,Yamakage, Shunichi,Takaku, Hiroshi,Hata, Tsujiaki
, p. 5713 - 5716 (2007/10/02)
The protection of the O6-amide and N2-amino groups of guanosine with the (butylthio)carbonyl group is described.This group could be rapidly introduced in good yields and removed very easily under the conventional deprotective conditi
CESIUM FLUORIDE PROMOTES SYNTHESYS OF RIBOOLIGONUCLEOTIDES VIA PHOSPHOTRIESTER APPROACH
Takaku, Hiroshi,Nomoto, Tadaaki,Murata, Mitsuho,Hata, Tsujiaki
, p. 1419 - 1422 (2007/10/02)
In the presence of cesium fluoride, the reactions of a fully protected 5'-O-dimethoxytrityl-2'-O-tetrahydropyranyl-N-acylnucleoside 3'-(4-chlorophenyl, 5-chloro-8-quinolyl) phosphates with 5'-hydroxyl nucleosides proceeded rapidly under mild conditions to afford the corresponding ribonucleoside monophosphates in good yields.
