76970-16-6

Upstream product

• 66548-63-8 6-(α,α,α-trifluoro-m-tolyl)-3-chloropyridazine 

Downstream Products

• 76970-00-8 3-(Trifluoromethyl)-6-(3-trifluoromethylphenyl)-1,2,4-triazolo[4,3-b]pyridazine 
• 102627-28-1 6-(3-(trifluoromethyl)phenyl)pyridazin-3-amine 
• 76970-02-0 3-(Methoxymethyl)-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine 
• 76970-01-9 3-(chloromethyl)-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-b]pyridazine 
• 78416-30-5 Chloro-acetic acid N'-[6-(3-trifluoromethyl-phenyl)-pyridazin-3-yl]-hydrazide 

Relevant academic research and scientific papers

Novel 6-phenyl and substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines

This disclosure describes novel 6-phenyl and substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines and their use as anxiolytic agents.

Synthesis and Anxiolytic Activity of 6-(Substituted-phenyl)-1,2,4-triazolopyridazines

The synthesis of a series of 6-(substituted-phenyl)-1,2,4-triazolopyridazines (VIII) is reported.Some of these derivatives show activity in tests predictive of anxiolytic activity (a) protection against pentylenetetrazole-induced convulsions; (b)