76972-23-1

Upstream product

• 76972-22-0 [5-(3,4-Dimethoxy-phenyl)-pyrimidin-2-yloxy]-acetic acid ethyl ester 
• 76972-10-6 2-chloro-5-(3,4-dimethoxyphenyl)pyrimidine 
• 33266-39-6 5-(3,4-dimethoxy-phenyl)-1-methyl-1H-pyrimidin-2-one 
• 270912-79-3 (5-bromopyrimidin-2-yloxy)acetic acid 
• 122775-35-3 3,4-Dimethoxyphenylboronic acid 

Downstream Products

• 642443-56-9 N-(1-tritylpiperidin-3-ylmethyl)-2-(5-(3,4-dimethoxyphenyl)pyrimidin-2-yloxy)acetamide 

Relevant academic research and scientific papers

2,5-substituted pyrimidine derivatives-CCR-3 receptor antagonists

This invention relates to certain pyrimidine derivatives that are CCR-3 receptor antagonists, pharmaceutical compositions containing them, methods for their use and methods for preparing these compounds.

Pyrimidones. 2. Synthesis and Reactions of 2-Chloropyrimidines

The treatment of 1-alkyl-5-aryl and 1-alkyl-4,5-diaryl-2-(1H)pyrimidones with phosphorus oxychloride and phosphorus pentachloride resulted in chlorination and dealkylation to furnish 2-chloro-5-aryl (or 4,5-diaryl)pyrimidines.These chloropyrimidines were