76988-65-3

Upstream product

• 58582-31-3 8-Chloro-1-(2-chlorophenyl)-3,4-dihydro-4-[(dimethylamino)methylene]-5H-2-benzazepin-5-one 
• 76049-70-2 8-chloro-1-(2-chlorophenyl)-3,4-dihydro-5H-2-benzazepin-5-one 
• 76049-78-0 8-chloro-1-(2-chlorophenyl)-3,4-dihydro-5H-2-benzazepin-5-one 2-oxide 
• 76988-39-1 9-chloro-7-(2-chlorophenyl)-5H-pyrimido<5,4-d><2>benzazepine 
• 3473-63-0 formamidine acetic acid 
• 76049-80-4 8-Chloro-1-(2-chloro-phenyl)-4-[1-dimethylamino-meth-(E)-ylidene]-2-oxy-3,4-dihydro-benzo[c]azepin-5-one 

Downstream Products

• 76988-67-5 9-chloro-7-(2-chlorophenyl)-5H-pyrimido<5,4-d><2>benzazepin-5-ol 
• 76988-66-4 9-chloro-7-(2-chlorophenyl)-5H-pyrimido<5,4-d><2>benzazepin-5-ol acetate 

Relevant academic research and scientific papers

2-Benzazepines. 5. Synthesis of pyrimido[5,4-d][2]benzazepines and their evaluation as anxiolytic agents

A series of 5H-pyrimido[5,4-d][2]benzazepines has been synthesized, starting from the corresponding 2-benzazepine-5-ones, and evaluated as potential anxiolytic agents. Selected compounds from this series show a pharmacological profile of action different

2-Benzazepines. 6. Synthesis and Pharmacological Properties of the Metabolites of 9-Chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine

The 2-benzazepine 9-chloro-7-(2-chlorophenyl)-5H-pyrimidobenzazepine (1) has been selected for development as an anxiolytic agent.In support of this program, we have confirmed by chemical synthesis the structures of three in vitro (rat liver hom