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2-[(3,3-DIPHENYLPROPYL)AMINO]ACETAMIDE HYDROCHLORIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

76991-05-4

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76991-05-4 Usage

Uses

N20C is a non-competitive NMDA receptor open-channel blocker.

Biological Activity

Selective, non-competitive NMDA receptor antagonist (IC 50 = 5 μ M); binds to the receptor-associated ion channel and prevents glutamate-induced Ca 2+ influx. In vivo, displays neuroprotective activity and is reported to be brain-penetrant.

Check Digit Verification of cas no

The CAS Registry Mumber 76991-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,9,9 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 76991-05:
(7*7)+(6*6)+(5*9)+(4*9)+(3*1)+(2*0)+(1*5)=174
174 % 10 = 4
So 76991-05-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H20N2O.ClH/c18-17(20)13-19-12-11-16(14-7-3-1-4-8-14)15-9-5-2-6-10-15;/h1-10,16,19H,11-13H2,(H2,18,20);1H

76991-05-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(3,3-diphenylpropylamino)acetamide,hydrochloride

1.2 Other means of identification

Product number -
Other names N20C hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76991-05-4 SDS

76991-05-4Downstream Products

76991-05-4Relevant academic research and scientific papers

A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity

Planells-Cases, Rosa,Montoliu, Carmina,Humet, Marc,Fernandez, Asia M.,Garcia-Martinez, Carolina,Valera, Elvira,Merino, Jaime M,Perez-Paya, Enrique,Messeguer, Angel,Felipo, Vicente,Ferrer-Montiel, Antonio

, p. 163 - 173 (2002)

Excitotoxicity has been implicated in the etiology of ischemic stroke, chronic neurodegenerative disorders, and very recently, in glioma growth. Thus, the development of novel neuroprotectant molecules that reduce excitotoxic brain damage is vigorously pu

Positional Scanning Synthesis of a Peptoid Library Yields New Inducers of Apoptosis that Target Karyopherins and Tubulin

Vendrell-Navarro, Glòria,Rúa, Federico,Bujons, Jordi,Brockmeyer, Andreas,Janning, Petra,Ziegler, Slava,Messeguer, Angel,Waldmann, Herbert

, p. 1580 - 1587 (2015)

We describe the synthesis of a library of 11 638 N-alkylglycine peptoid trimers in a positional scanning format with adjustment of reaction conditions to account for different reactivities of the monomer building blocks. Evaluation of the library by high-content phenotypic screening for modulators of the cytoskeleton and mitosis resulted in the identification of two apoptosis-inducing peptoids, which, despite their structural similarity, target different proteins and cellular mechanisms. Whereas one peptoid binds to karyopherins, which mediate nuclear transport, the other N-alkylglycine trimer binds tubulin at the vinca alkaloid binding site.

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