769918-25-4Relevant academic research and scientific papers
2,3-Disubstituted quinuclidines as a novel class of dopamine transporter inhibitors
Sakamuri, Sukumar,Enyedy, Istvan J.,Zaman, Wahiduz A.,Tella, Srihari R.,Kozikowski, Alan P.,Flippen-Anderson, Judith L.,Farkas, Tivadar,Johnson, Kenneth M.,Wang, Shaomeng
, p. 1123 - 1136 (2007/10/03)
There is considerable interest in developing dopamine transporter (DAT) inhibitors as potential therapies for the treatment of cocaine abuse. We report herein our pharmacophore-based discovery and molecular modeling-assisted rational design of 2,3-disubst
