769931-69-3Relevant academic research and scientific papers
Inositols as chiral templates: 1,4-conjugate addition to tethered cinnamic esters.
Cousins, Ghislaine,Falshaw, Andrew,Hoberg, John O
, p. 2272 - 2274 (2004)
The 1,4-addition of thio nucleophiles to chiro-inositols containing a cinnamyl Michael acceptor proceeded with excellent diastereochemical induction and good yields. Cleavage of the inositol auxiliary provides beta-thio hydrocinnamic acids in >99% ee's.
