76994-79-1

Basic information

• Product Name: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[6-(2,4,6-trimethyl-benzenesulfonyloxy)-2-(trityl-amino)-purin-9-yl]-tetrahydro-furan-3-yl ester
• Synonyms: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[6-(2,4,6-trimethyl-benzenesulfonyloxy)-2-(trityl-amino)-purin-9-yl]-tetrahydro-furan-3-yl ester
• CAS NO: 76994-79-1
• Molecular Weight: 833.919
• Mol File: 76994-79-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[6-(2,4,6-trimethyl-benzenesulfonyloxy)-2-(trityl-amino)-purin-9-yl]-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[6-(2,4,6-trimethyl-benzenesulfonyloxy)-2-(trityl-amino)-purin-9-yl]-tetrahydro-furan-3-yl ester(76994-79-1)
• EPA Substance Registry System: Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[6-(2,4,6-trimethyl-benzenesulfonyloxy)-2-(trityl-amino)-purin-9-yl]-tetrahydro-furan-3-yl ester(76994-79-1)

Safety Data

• Hazardous Substances Data: 76994-79-1(Hazardous Substances Data)

Upstream product

• 773-64-8 2-mesitylenesulphonyl chloride 
• 69471-51-8 2',3',5'-Tri-O-acetyl-N²-tritylguanosine 
• 69471-51-8 2',3',5'-tri-O-acetyl-N²-tritylguanosine 

Downstream Products

• 76994-81-5 Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[2-amino-6-(2,4,6-triisopropyl-benzenesulfonyloxy)-purin-9-yl]-tetrahydro-furan-3-yl ester 
• 66107-69-5 9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-6-O-p-toluenesulfonylguanine 
• 6979-94-8 2-amino-6-hydroxyl-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine 
• 66107-67-3 2',3',5-tri-O-acetyl-O⁶-meritylsulfonylguanosine 
• 66107-67-3 Acetic acid (3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-[2-amino-6-(2,4,6-trimethyl-benzenesulfonyloxy)-purin-9-yl]-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Synthesis and Properties of O6-Substituted Guanosine Derivatives

Reactions of 2',3',5'-tri-O-acetyl-N2-protected or unprotected guanosine derivatives with phosphoryl, phosphinothioyl, arylsulfonyl, and silyl halides in dichloromethane gave the corresponding O6-substituted guanosine derivatives in good yields.In these reactions, 4-(dimethylamino)pyridine (DMAP) was found to be very effective catalyst.The physical data of these products and their stabilities under acidic and basic conditions were described in detail.Selective detritylation of O6-arylsulfonyl-N2-tritylguanosinde derivatives was accomplished by treatment with 80percent aceti c acid.It was found that O6-dibutylphosphinothioyl derivatives were relatively stable under conditions where acetyl group was predominantly removed.