769944-51-6

Usage

Uses

Used in Pharmaceutical Research:
4-CPP is utilized as a research chemical for studying the effects of selective serotonin receptor agonism on conditions such as anxiety and depression. Its interaction with the serotonin system provides insights into the development of novel treatments for mood disorders.
Used in Migraine and Cluster Headache Treatment Research:
In the medical field, 4-CPP is explored as a potential therapeutic agent for the treatment of migraines and cluster headaches. Its agonistic action on specific serotonin receptors suggests a possible role in managing the symptoms and underlying mechanisms of these conditions.
Used in Neuroscientific Research:
4-CPP's serotonergic activity also makes it a valuable tool in neuroscientific research, where it can be employed to investigate the role of serotonin in various physiological and neurological processes, contributing to a better understanding of the neurotransmitter's function in the brain.
Used in Drug Development:
2-(4-chlorophenyl)piperazine's selectivity for certain serotonin receptors indicates its potential use in the development of new drugs targeting specific conditions. Researchers may leverage 4-CPP's properties to create medications with fewer side effects and greater efficacy.

InChI:InChI=1/C11H14ClN/c12-10-6-4-9(5-7-10)11-3-1-2-8-13-11/h4-7,11,13H,1-3,8H2/t11-/m0/s1

Upstream product

• 1185157-51-0 (R)-2-(4-chlorophenyl)piperazine dihydrochloride 

Relevant academic research and scientific papers

METHOD FOR PRODUCING OPTICALLY ACTIVE 2-ARYLPIPERAZINE DERIVATIVE

The objective of the present invention is to produce an optically active 2-arylpiperazine derivative useful as a synthetic intermediate for pharmaceutical products and agricultural chemicals from inexpensive and readily available starting material by an industrially practicable method. The objective can be accomplished by treating an optically active substituted aminodiol derivative produced from an optically active styrene oxide derivative with a sulfonating agent in the presence of a base, and then reacting an amine compound to obtain the 2-arylpiperazine derivative. Especially, an optically active 1-unsubstituted-2-arylpiperazine derivative can be produced by treating an optically active 1-allyl-2-arylpiperazine derivative with water in the presence of a transition metal catalyst for deallylation.

2, 3, 6-TRISUBSTITUTED-4-PYRIMIDONE DERIVATIVES

A pyrimidone derivative having tau protein kinase 1 inhibitory activity which is represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof; useful for prventive and/or therapeutic treatment of diseass such as neurodegenerative diseases (e.g. Alzheimer disease); wherein Q represents CH or nitrogen atom; R represents a C1-C12 alkyl group; the ring of Formula (I): represents piperazine ring or piperidine ring; each X independently represents a C1-C8 alkyl group, an optionally partially hydrogenated C6-C10 aryl ring, an indan ring or the like; m represents an integer of 1 to 3; each Y independently represents a halogen atom, a hydroxy group, a cyano group, a C1-C6 alkyl group or the like; n represents an integer of 0 to 8; when X and Y or two Y groups are attached on the same carbon atom, they may combine to each other to form a C2-C6 alkylene group.