769968-48-1Relevant academic research and scientific papers
One-step synthesis of quinazolino[3,2-a ]quinazolinones via palladium-catalyzed domino addition/carboxamidation reactions
Zeng, Fanlong,Alper, Howard
supporting information; experimental part, p. 3642 - 3644 (2010/10/02)
A highly efficient palladium-catalyzed domino process has been developed for the synthesis of quinazolino[3,2-a]quinazolinones by forming five new bonds in a single step. Despite the high density and variety of functional groups on the substrates, the tetracyclic quinazolinones were obtained in good to excellent yields.
