769972-03-4Relevant academic research and scientific papers
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents
Ismail, Mohamed A.,Brun, Reto,Wenzler, Tanja,Tanious, Farial A.,Wilson, W. David,Boykin, David W.
, p. 5405 - 5413 (2004)
A series of biphenyl benzimidazoles diamidines 6a-i were synthesized from their respective diamidoximes, through the bis-O-acetoxyamidoxime followed by hydrogenation in glacial acetic acid/ethanol in the presence of Pd-C. The target compounds contain hydr
DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS
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Page/Page column 51-52, (2008/06/13)
Novel dicationic, heterocyclic triaryl compounds are useful in the treatment of microbial infections, such as Trypanosoma brucei rhodesiense infection and Plasmodium falciparum infection. These compounds are accordingly useful in treating second-stage human African trypanosomiasis. Pharmaceutical formulations comprising these compounds can be used in methods of treating microbial infections.
