77006-29-2 Usage
Uses
Used in Pharmaceutical Industry:
AMPA is utilized as a research compound for understanding the mechanisms of synaptic transmission and plasticity. Its agonistic properties are leveraged to investigate the role of AMPA receptors in cognitive functions and neurological disorders.
Used in Neurological Research:
In the field of neuroscience, AMPA serves as a crucial tool in studying the pathophysiology of conditions like epilepsy and stroke, where AMPA receptor activity is implicated. It aids in the development of therapeutic strategies targeting these receptors to manage or treat such disorders.
Used in Drug Development:
AMPA and its analogs are explored as potential therapeutic agents for a range of neurological conditions. Their modulation of AMPA receptors offers opportunities for the treatment of cognitive impairments and other symptoms associated with neurodegenerative diseases.
Used in Cognitive Enhancement Therapies:
AMPA's influence on learning and memory makes it a candidate for cognitive enhancement therapies, where its agonistic effects on AMPA receptors could potentially improve cognitive performance in conditions characterized by cognitive decline.
Check Digit Verification of cas no
The CAS Registry Mumber 77006-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,0,0 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77006-29:
(7*7)+(6*7)+(5*0)+(4*0)+(3*6)+(2*2)+(1*9)=122
122 % 10 = 2
So 77006-29-2 is a valid CAS Registry Number.
77006-29-2Relevant academic research and scientific papers
Nitrile Oxide Cycloaddition of Non-activated Alkynes: A Novel Approach to the Synthesis of Neuroactive Isoxazoles
Pevarello, Paolo,Amici, Raffaella,Colombo, Maristella,Varasi, Mario
, p. 2151 - 2152 (2007/10/02)
A general method for the unprecedented 1,3-dipolar cycloaddition of bromonitrile oxide to distributed non-activated alkynes provides a useful alternative route to the neuropharmacological tools AMPA and 4-methylhomoibotenic acid.
