7701-14-6Relevant academic research and scientific papers
Structure-activity relationship of naphthaldehydethiosemicarbazones in melanogenesis inhibition
Thanigaimalai, Pillaiyar,Rao, Eeda Venkateswara,Lee, Ki-Cheul,Sharma, Vinay K.,Roh, Eunmiri,Kim, Youngsoo,Jung, Sang-Hun
scheme or table, p. 886 - 889 (2012/03/26)
2-(Naphthalen-1-ylmethylene)hydrazinecarbothioamide (14, IC50 = 1.1 μM) was discovered as a highly potent inhibitor of melanogenesis. To define the role of hydrogens (at N1 and N3) and sulfur in 14, a series of analogs 15a-p were synthesized an
