77015-91-9Relevant academic research and scientific papers
Bausteine von Oligosacchariden, XXI. Synthesen von Gentamicin X2 und am C-4' und C-3' modifizierter Gentamicine
Paulsen, Hans,Schroeder, Bernd,Boettcher, Henning,Hohlweg, Rolf
, p. 322 - 332 (2007/10/02)
The garamine derivative 18 can be coupled with the β-chloride 15 of 2-azido-2-deoxy-D-glucose to 20 from which, by deblocking procedure, gentamicin X2 (23) is available.In the same manner the 4'-amino- and 4'-chloro compound 24 and 25, resp., can be obtained.Coupling of 26 with 19 gives the product 27 from which the derivative 28 of gentamicin, modified at C-3', is prepared.
