770714-52-8

Upstream product

• 713521-72-3 (R)-2-[(1R,3aR,4S,7aR)-4-(tert-butyldimethylsilanyloxy)-7a-methyloctahydroinden-1-yl]-6-methylheptane-1,6-diol 
• 792959-69-4 (R)-6-[(1R,3aR,4S,7aR)-4-(tert-butyl-dimethyl-silanyloxy)-7a-methyl-octahydro-inden-1-yl]-2-methyl-7-phenylsulfanyl-heptan-2-ol 
• 792959-67-2 [1R,3aR,4S,7aR]-5(R,S)-benzenesulfonyl-6(S)-[4-(tert-butyldimethylsillanyloxy)-7a-methyl-octahydro-inden-1-yl]-2,10-dimethyl-undecane-2,3(R),10-triol 
• 770714-57-3 (1R,3aR,4S,7aR)-1-((R)-1-benzenesulfonylmethyl-5-methyl-5-trimethylsilanyloxyhexyl)-4-(tert-butyldimethylsilanyloxy)-7a-methyloctahydroindene 
• 792959-68-3 (3R,6R)-6-[(1R,3aR,4S,7aR)-4-(tert-butyldimethylsilanyloxy)-7a-methyloctahydroinden-1-yl]-2,10-dimethylundecane-2,3,10-triol 
• 770714-48-2 (R)-7-benzenesulfonyl-6-[(1R,3aR,4S,7aR)-4-(tert-butyldimethylsilanyloxy)-7a-methyloctahydroinden-1-yl]-2-methylheptan-2-ol 
• 713521-95-0 (R)-6-[(1R,3aR,4S,7aR)-4-(tert-butyldimethylsilanyloxy)-7a-methyloctahydroinden-1-yl]-7-iodo-2-methylheptan-2-ol 
• 77522-15-7 (2R)-2,3-dihydroxy-3-methylbutan-1-yl p-toluenesulfonate 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 770714-51-7 (1R,3aR,4S,7aR)-1-((S)-5-hydroxy-1-{2-[(R)-2-(4-methoxyphenyl)-5,5-dimethyl-[1,3]dioxan-4-yl]ethyl}-5-methylhexyl)-7a-methyloctahydroinden-4-ol 

Downstream Products

• 827032-53-1 [1R,3aR,7aR,4E]-4-{2(Z)-[3(S),5(R)-bis-(tert-butyl-dimethyl-silanyloxy)-cyclohexylidene]-ethylidene}-7a-methyl-1-[5-methyl-1(S)-(4-methyl-4-triethylsilanyloxy-pentyl)-4(R),5-bis-triethylsilanyloxy-hexyl]-octahydro-indene 
• 770714-54-0 (1R,3aS,7aR)-4(E)-{2-[(R)-3-((R)-(tert-butyldimethylsilyloxy))-5-(tert-butyldimethylsilyloxy)cyclohexylidene]ethylidene}-7a-methyl-1-[(1S,4R)-5-methyl-1-(4-methyl-4-(triethylsilanyloxy)pentyl)-4,5-bis(triethylsilanyloxy)hexyl]octahydroindene 

Relevant academic research and scientific papers

GEMINI VITAMIN D3 COMPOUNDS AND METHODS OF USE THEREOF

The invention provides Gemini vitamin D3 compounds, methods for using the compounds to treat vitamin D3 associated states and pharmaceutical compositions containing the compounds.

USE OF VITAMIN D COMPOUNDS TO TREAT ENDOMETRIOSIS

The use of vitamin D compounds in the treatment or prevention of endometriosis, methods for the treatment or prevention of endometriosis by administering a vitamin D compound, and compounds for use therein.

COMBINED USE OF VITAMIN D DERIVATIVES AND ANTI-PROLIFERATIVE AGENTS FOR TREATING BLADDER CANCER

There is provided according to the invention a method of treating a patient with bladder cancer by administering a effective amount of a vitamin D compound in combination with one or more other antiproliferative agents. Also provided are uses of a vitamin

Calcitriol derivatives with two different side chains at C-20. II. Diastereoselective syntheses of the metabolically produced 24(R)-hydroxygemini

Vitamin D derivatives containing two side chains emanating at C-20 are known as gemini. We have recently synthesized two gemini which are related to calcitriol and 19-norcalcitriol containing two identical side chains. The metabolism of these species invo