770735-90-5

Upstream product

• 478175-78-9 benzyl 4-cyano-4-deoxy-2,3-O-isopropylidene-α-D-arabinoside 
• 478175-66-5 benzyl 2,3-O-isopropylidene-β-L-xylopyranoside 
• 478175-76-7 benzyl 4-O-(imidazol-1-ylsulfonyl)-2,3-O-isopropylidene-β-L-xylopyranoside 

Downstream Products

• 770735-92-7 Acetic acid (2R,3S,4R,5R)-4-acetoxy-2-benzyloxy-5-cyano-tetrahydro-pyran-3-yl ester 
• 770735-95-0 (3R,4R,5S,6R)-6-Benzyloxy-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran-3-carbonitrile 
• 478175-82-5 benzyl 4C-[(tert-butoxycarbonyl)amino]methyl-4-deoxy-α-D-arabinopyranoside 
• 1004553-75-6 benzyl 3-O-benzoyl-4-C-cyano-4-deoxy-α-D-arabinoside 
• 958001-19-9 benzyl 4C-[(tert-butoxycarbonyl)amino]methyl-2,3-di-O-(tert-butyldimethylsilyl)-4-deoxy-α-D-arabinopyranoside 
• 958001-21-3 benzyl 4C-[(tert-butoxycarbonyl)amino]methyl-4-deoxy-2,3-bis-O-(trimethylsilyl)-α-D-arabinopyranoside 

Relevant academic research and scientific papers

Improvements to the synthesis of isofagomine, noeuromycin, azafagomine, and isofagomine lactam, and a synthesis of azanoeuromycin and guanidine isofagomine

Improvements in the preparation of a key imidazylate and the reduction of the derived nitrile have led to more efficient syntheses of isofagomine, noeuromycin, azafagomine, and isofagomine lactam. As well, a precursor of azafagomine has been converted int

The synthesis of a D-glucose-like piperidin-2-one: Isofagomine lactam

Benzyl 4-cyano-4-deoxy-α-D-arabinoside was converted into both its 2,3-di-O-acetyl and 2,3-di-O-(tert-butyldimethylsilyl) derivatives. The latter, by a process of hydrogenolysis, oxidation, and methanolysis, gave methyl 2,3-di-O-(tert-butyldimethylsilyl)-