77084-15-2

Usage

Uses

Used in Pharmaceutical Development:
(2-PHENYL-1-BENZOFURAN-5-YL)AMINE is used as a precursor in the development of new drugs due to its potential pharmacological properties and the diverse biological activities associated with the benzofuran scaffold.
Used in Anticancer Applications:
In the pharmaceutical industry, (2-PHENYL-1-BENZOFURAN-5-YL)AMINE is used as a potential anticancer agent, leveraging its biological activities to target and combat cancer cells.
Used in Anti-inflammatory Applications:
(2-PHENYL-1-BENZOFURAN-5-YL)AMINE is utilized as an anti-inflammatory agent, taking advantage of its capacity to reduce inflammation and alleviate related symptoms.
Used in Antiviral Applications:
In the field of virology and pharmaceuticals, (2-PHENYL-1-BENZOFURAN-5-YL)AMINE is employed as an antiviral agent, harnessing its properties to inhibit viral replication and reduce the severity of viral infections.

InChI:InChI=1/C14H11NO/c15-12-6-7-13-11(8-12)9-14(16-13)10-4-2-1-3-5-10/h1-9H,15H2

Upstream product

• 16237-97-1 5-nitro-2-phenylbenzofuran 

Downstream Products

• 77084-16-3 5-N-acetylamino-2-phenylbenzofuran 
• 1314147-62-0 C₂₃H₂₆N₂O₃ 
• 1314147-61-9 C₂₃H₂₆N₂O₃ 

Relevant academic research and scientific papers

Novel anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production

Heterocyclic amidines with anti-inflammatory and analgesic activity that inhibit nitrogen oxide production, of formula (I): in which: G1 and G2 are hydrogen, halogen, hydroxyl, C1-C4 alkoxy, C1-C4 alkyl, and an amidino substituent of formula Q, provided that, for each compound of formula (I), only one of the two substituents G1 or G2 is an amidino substituent of formula Q: and in which the substituents W, Y and X are combined to form 9- or 10-membered bicyclic heteroaromatic derivatives containing up to 2 hetero atoms in the same ring; and Z is an aryl or heteroaryl group, a linear or branched C1-C6 alkyl or alkenyl chain, a C1-C4 alkyl-aryl group or a C1-C4 alkyl-heteroaryl group.

Novel anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production

Heterocyclic amidines with anti-inflammatory and analgesic activity that inhibit nitrogen oxide production, of formula (I): in which:G1 and G2 are hydrogen, halogen, hydroxyl, C1-C4 alkoxy, C1-C4 alkyl, and an amidino substituent of formula Q, provided that, for each compound of formula (I), only one of the two substituents G1 or G2 is an amidino substituent of formula Q: and in which the substituents W, Y and X are combined to form 9- or 10-membered bicyclic heteroaromatic derivatives containing up to 2 hetero atoms in the same ring; andZ is an aryl or heteroaryl group, a linear or branched C1-C6 alkyl or alkenyl chain, a C1-C4 alkyl-aryl group or a C1-C4 alkyl-heteroaryl group.

Chemistry of aminophenols. Part 3: First synthesis of nitrobenzo[b]furans via a coupling-cyclization approach

The first synthesis of 4-, 5-, and 6-nitrobenzo[b]furans has been achieved via the Sonogashira cross-coupling reaction of 2-iodonitrophenol acetates prepared from commercially available and inexpensive 2-aminonitrophenols. The obtained 2-alkynylnitropheno

Compounds derived from 3-(benzofuran-5-yl)oxazolidin-2-one, preparation method therefor and therapeutical use thereof

PCT No. PCT/FR96/01731 Sec. 371 Date May 8, 1998 Sec. 102(e) Date May 8, 1998 PCT Filed Nov. 5, 1996 PCT Pub. No. WO97/17346 PCT Pub. Date May 15, 1997Compounds derived from 3-(benzofuran-5-yl) oxazolidin-2-one, of general formula (I) in which: R1 represe