77086-19-2 Usage
Uses
Biochemical probe for NMDA receptors.
General Description
(-)-MK-801 hydrogen maleate is a less potent stereoisomer of (+)-MK-801.
Biological Activity
Less active enantiomer (10-fold less potent in behavioral studies) than (+)-MK 801 maleate ((5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate ).
Biochem/physiol Actions
Less active enantiomer of (+)-MK-801 hydrogen maleate
Check Digit Verification of cas no
The CAS Registry Mumber 77086-19-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,0,8 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 77086-19:
(7*7)+(6*7)+(5*0)+(4*8)+(3*6)+(2*1)+(1*9)=152
152 % 10 = 2
So 77086-19-2 is a valid CAS Registry Number.
77086-19-2Relevant articles and documents
Intermolecular Radical C(sp3)?H Amination under Iodine Catalysis
Bosnidou, Alexandra E.,Mu?iz, Kilian
, p. 7485 - 7489 (2019/04/30)
The direct amination of aliphatic C?H bonds has remained one of the most tantalizing transformations in organic chemistry. Herein, we report on a unique catalyst system, which enables the elusive intermolecular C(sp3)?H amination. This practical synthetic strategy provides access to aminated building blocks and fosters innovative multiple C?H amination within a new approach to aminated heterocycles. The synthetic utility is demonstrated by the synthesis of four relevant pharmaceuticals.