77087-93-5

Upstream product

• 135370-45-5 2,6-diphenyl-4-(β-methoxystyryl)-3-azapyrylium trifluoromethanesulfonate 
• 135370-43-3 2,6-diphenyl-4-benzoylmethylene-1,3-oxazine 
• 77087-85-5 2-Benzoylamino-2-phenacyl-4-phenyl-4-oxobutansaeure 
• 77087-77-5 4,4-Diphenacyl-2-phenyl-2-oxazolin-5-on 
• 1199-01-5 2-phenylazlactone 
• 495-69-2 Hippuric Acid 

Relevant academic research and scientific papers

ACID-CATALYZED ACYLATION OF 4-ALKYL-3-AZAPYRYLIUM SALTS AND THE SYNTHESIS OF 4-ACYLAMINOPYRYLIUM SALTS

4-Alkyl-3-azapyrylium salts undergo acylation at the alkyl group under acid-catalyzed conditions to give 4-acylmethyl-3-azapyrylium derivatives, which upon heating in proton-donating solvents recyclize to give 4-acylaminopyrylium salts.

α-Amino Acids as Nucleophilic Acyl Equivalents, IV. Synthesis of Symmetrical Ketones by Means of 2-Phenyl-2-oxazolin-5-one

2-Phenyl-2-oxazolin-5-one (2), itself easily derivable from hippuric acid (1), on reaction with allyl, benzyl or phenacyl halides undergoes 4,4-disubstitution, if the reaction is conducted in dipolar aprotic solvents in presence of weak bases.Hydrolysis of the resulting oxazolinones 3 leads to α,α-dialkylaed hippuric acids 4, which may be oxidized to symmetrical ketones 5 by means of lead tetraacetate.