77093-91-5Relevant academic research and scientific papers
2-Phenyl-(6(7)-R-substituted quinoxalines N-oxides. Synthesis, structure elucidation and antimicrobial activity
Loriga,Nuvole,Paglietti,Fadda,Zanetti
, p. 527 - 532 (2007/10/02)
A certain number of isomeric 2-phenylquinoxalines N-oxides bearing substituents at position 6/7 were prepared in order to investigate anti-microbial activity. The effect of some electron-withdrawing groups seem to increase an anti-Trichomonas vaginalis ac
Synthesis of Quinoxaline Derivatives through Condensation of 1,2-Diaminobenzenes with β-Keto Sulfoxides
Kano, Shinzo,Shibuya, Shiroshi,Yuasa, Yoko
, p. 1559 - 1561 (2007/10/02)
The reaction of o-phenylenediamine with α-methylsulfinylcyclohexanone and α-methylsulfinylcyclopentanone in the presence of acetic acid afforded 1,2,3,4-tetrahydrophenazine and 2,3-dihydro-1H-cyclopentaquinoxaline, respectively. 3,4-Diaminotoluene and 3,4-diaminochlorobenzene were reacted with α-methylsulfinylacetophenone to give a mixture of the corresponding 6- and 7-substituted 2-phenylquinoxaline.Condensation of 3,4-diaminomethoxybenzene with α-methylsulfinylacetophenone gave 7-methoxy-2-phenylacetophenone, whereas, the same reaction between 3,4-diaminonitrobenzene and α-methylsulfinylacetophenone yielded 6-nitro-2-phenylquinoxaline.
