77094-05-4Relevant articles and documents
Syntheses of 2-Amino-3,4-dimethyl-3H-imidazoquinoline and Its Related Compounds
Kasai, Hiroshi,Nishimura, Susumu
, p. 2233 - 2235 (2007/10/02)
The strongly mutagenic compound, 2-amino-3,4-dimethyl-3H-imidazoquinoline (Me-IQ), isolated from broiled sardines was synthesized from 6-amino-7-methylquinoline.Several structurally related compounds were also synthesized to clarify the structure-a
STRUCTURE AND CHEMICAL SYNTHESIS OF ME-IQ, A POTENT MUTAGEN ISOLATED FROM BROILED FISH
Kasai, Hiroshi,Yamaizumi, Ziro,Wakabayashi, Keiji,Nagao, Minako,Sugimura, Takashi,et al.
, p. 1391 - 1394 (2007/10/02)
Structure of a mutagenic compound (Me-IQ) isolated from broiled fish was determined to be 2-amino-3,4-dimethylimidazoquinoline based on the mass-, UV- and 1HNMR-spectra and chemical synthesis.Me-IQ showed strong mutagenic activity towards Salmonella typhimurium TA98 in the presence of S-9 mix.