Troponin I, a protein found in skeletal and cardiac muscle, plays a crucial role in muscle contraction regulation. It is a component of the troponin complex, which is responsible for controlling the interaction between actin and myosin, the two main proteins involved in muscle contraction. Troponin I's function is to inhibit the actin-myosin interaction in the absence of calcium, ensuring that muscle contraction only occurs when needed.
77108-40-8
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Basic information
- Product Name: TROPONIN I
- Synonyms: troponin I from human heart;Recombinant Human Cardiac Troponin-I;TroponinI from human heart,Tn-I;HCTNL;TROPONIN I-SKELETAL, HUMAN;TROPONIN I;TROPONIN I (CARDIAC);TROPONIN I-CARDIAC, HUMAN
- CAS NO:77108-40-8
- Molecular Formula: NULL
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: proteins
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /lyophilized powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: TROPONIN I(CAS DataBase Reference)
- NIST Chemistry Reference: TROPONIN I(77108-40-8)
- EPA Substance Registry System: TROPONIN I(77108-40-8)
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Safety Data
- Hazard Codes: B
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 77108-40-8(Hazardous Substances Data)
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77108-40-8 Usage
Uses
Used in Medical Research:Troponin I is used as a biomarker for [detecting myocardial injury or infarction] in [cardiac stress testing and diagnosing heart attacks]. Its presence in the blood indicates damage to the heart muscle, making it a valuable tool for monitoring heart health and assessing the effectiveness of treatments.
Used in Biochemistry Studies:
Troponin I is used as a research subject for [investigating the regulatory mechanisms of muscle contraction] in [understanding the complex interactions between actin, myosin, and other proteins involved in muscle function]. This helps scientists gain insights into the molecular basis of muscle diseases and develop potential therapeutic strategies.
Used in Enzyme Interaction Studies:
Troponin I from human heart can be used as a research tool for [studying the protective effects of actin and aldolase on rabbit muscle lactate dehydrogenase inhibition by ascorbate] in [exploring the role of these proteins in enzyme stability and function]. This can provide valuable information on the interplay between different muscle proteins and their influence on enzymatic activities.
Biochem/physiol Actions
Troponin I interacts with tropomyosin for regulating the contraction of striated muscle in a calcium-dependent manner. Additionally, Troponin I can also inhibits actomyosin ATPase and serves as a selective and potent inhibitor of angiogenesis in vivo and in vitro and of tumor metastasis in vivo.Check Digit Verification of cas no
The CAS Registry Mumber 77108-40-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,0 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.Calculate Digit Verification of CAS Registry Number 77108-40:
(7*7)+(6*7)+(5*1)+(4*0)+(3*8)+(2*4)+(1*0)=128
128 % 10 = 8
So 77108-40-8 is a valid CAS Registry Number.
77108-40-8Upstream product
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TROPONIN I
